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    smg5 SMG5 nonsense mediated mRNA decay factor [ Neolamprologus brichardi ]

    Gene ID: 102797181, updated on 10-Mar-2024

    Summary

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    Gene symbol
    smg5
    Gene description
    SMG5 nonsense mediated mRNA decay factor
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Neolamprologus brichardi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Lamprologini; Neolamprologus
    Orthologs
    human zebrafish all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    101 current NeoBri1.0 (GCF_000239395.1) Unplaced Scaffold NW_006272084.1 (1367440..1391047)

    NW_006272084.1Genomic Context describing neighboring genes Neighboring gene PHD finger protein 1 Neighboring gene synaptic Ras GTPase activating protein 1b Neighboring gene progestin and adipoQ receptor family member VI Neighboring gene neurotrophic tyrosine kinase, receptor, type 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_006272084 Unplaced Scaffold Reference NeoBri1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomerase RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of telomerase holoenzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein SMG5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Neolamprologus brichardi Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NeoBri1.0 Primary Assembly

    Genomic

    1. NW_006272084.1 Reference NeoBri1.0 Primary Assembly

      Range
      1367440..1391047
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035912526.1 → XP_035768419.1  protein SMG5

      UniProtKB/TrEMBL
      A0A3Q4GQ84
      Conserved Domains (3) summary
      cd09884
      Location:953 → 1078
      PIN_Smg5-like; VapC-like PIN domain of human nonsense-mediated decay factor Smg5, and other similar eukaryotic homologs
      pfam10373
      Location:194 → 400
      EST1_DNA_bind; Est1 DNA/RNA binding domain
      pfam10374
      Location:74 → 185
      EST1; Telomerase activating protein Est1
    Nucleotide Protein
    Heading Accession and Version

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