U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit [ Mus musculus (house mouse) ]

    Gene ID: 12291, updated on 2-May-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Cacna1gprovided by MGI
    Official Full Name
    calcium channel, voltage-dependent, T type, alpha 1G subunitprovided by MGI
    Primary source
    MGI:MGI:1201678
    See related
    Ensembl:ENSMUSG00000020866 AllianceGenome:MGI:1201678
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    a1G; [a]1G; Cav3.1d; alpha-1G; mKIAA1123
    Summary
    Enables low voltage-gated calcium channel activity; voltage-gated calcium channel activity involved SA node cell action potential; and voltage-gated calcium channel activity involved in AV node cell action potential. Involved in calcium ion transmembrane transport; cardiac conduction; and cardiac muscle cell action potential involved in contraction. Acts upstream of or within several processes, including regulation of atrial cardiac muscle cell membrane depolarization; regulation of heart rate; and response to nickel cation. Located in plasma membrane. Part of voltage-gated calcium channel complex. Is expressed in central nervous system; heart; hindlimb musculature; lower jaw molar; and retina. Used to study cerebellar ataxia type 42. Human ortholog(s) of this gene implicated in cerebellar ataxia type 42. Orthologous to human CACNA1G (calcium voltage-gated channel subunit alpha1 G). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in limb E14.5 (RPKM 50.1), cerebellum adult (RPKM 19.2) and 10 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    11 D; 11 58.9 cM
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94299217..94365226, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94408391..94474400, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7046 Neighboring gene ankyrin repeat domain 40 Neighboring gene ATP-binding cassette, sub-family C member 3 Neighboring gene predicted gene, 51871 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:94235659-94235882 Neighboring gene STARR-seq mESC enhancer starr_30466 Neighboring gene STARR-seq mESC enhancer starr_30467 Neighboring gene STARR-seq mESC enhancer starr_30468 Neighboring gene predicted gene, 51872 Neighboring gene STARR-positive B cell enhancer ABC_E10707 Neighboring gene spermatogenesis associated 20 Neighboring gene epsin 3 Neighboring gene predicted gene, 51873

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ataxic phenotype with altered Ca(V)3.1 channel property in a mouse model for spinocerebellar ataxia 42. Hashiguchi S, et al. Neurobiol Dis, 2019 Oct. PMID 31229688
    2. Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia. Timic Stamenic T, et al. Cereb Cortex, 2019 Dec 17. PMID 30715245, Free PMC Article
    3. α(1G) T-type calcium channel determines the angiogenic potential of pulmonary microvascular endothelial cells. Zheng Z, et al. Am J Physiol Cell Physiol, 2019 Mar 1. PMID 30649917, Free PMC Article
    4. Increasing T-type calcium channel activity by β-adrenergic stimulation contributes to β-adrenergic regulation of heart rates. Li Y, et al. J Physiol, 2018 Apr 1. PMID 29274077, Free PMC Article
    5. T-type voltage gated calcium channels are involved in endothelium-dependent relaxation of mice pulmonary artery. Gilbert G, et al. Biochem Pharmacol, 2017 Aug 15. PMID 28438566

    See all (127) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Downregulation of Cav3.1 T-type Calcium Channel Expression in Age-related Hearing Loss Model.
      Title: Downregulation of Cav3.1 T-type Calcium Channel Expression in Age-related Hearing Loss Model.
    2. Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.
      Title: Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.
    3. Concomitant genetic ablation of L-type Cav1.3 (alpha1D) and T-type Cav3.1 (alpha1G) Ca(2+) channels disrupts heart automaticity.
      Title: Concomitant genetic ablation of L-type Ca(v)1.3 (α(1D)) and T-type Ca(v)3.1 (α(1G)) Ca(2+) channels disrupts heart automaticity.
    4. Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia.
      Title: Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia.
    5. Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.
      Title: Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.
    6. T-type channels Cav3.1and Cav3.2 do not contribute to baseline blood pressure levels and ANG II-induced hypertension. Cav3.1, but not Cav3.2, contributes to aldosterone secretion. Aldosterone promotes cardiac hypertrophy during hypertension.
      Title: Deficiency of T-type Ca(2+) channels Ca(v)3.1 and Ca(v)3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.
    7. Loss of Cav3.1 makes the beating rates of the heart in vivo and perfused hearts ex vivo, as well as sinoatrial node cells, less sensitive to beta-adrenergic stimulation.
      Title: Increasing T-type calcium channel activity by β-adrenergic stimulation contributes to β-adrenergic regulation of heart rates.
    8. Results confirm the idea that T-channels critically support rebound burst firing following periods of membrane hyperpolarization, similar to those that occur during inhibitory synaptic potentials in the ventral tegmental area. Behavioral results indicate that deletion of CaV3.1 channels disrupts the hyperlocomotion.
      Title: Ca(V)3.1 isoform of T-type calcium channels supports excitability of rat and mouse ventral tegmental area neurons.
    9. Cav3.1 expression was significantly reduced in aortae from aged compared to young WT mice. The level of phosphorylated eNOS was significantly increased in aortae from aged Cav3.1-/- mice. Cav3.1-deficient mice develop less age-dependent endothelial dysfunction.
      Title: Deletion of T-type calcium channels Ca(v)3.1 or Ca(v)3.2 attenuates endothelial dysfunction in aging mice.
    10. FMOD affected the expressions of the Cav1.1 and Cav3.1 genes. FMOD regulates calcium channel activity. The mRNA expressions of Cav1.1 and Cav3.1 increased during muscle regeneration.
      Title: Fibromodulin modulates myoblast differentiation by controlling calcium channel.
    Submit: New GeneRIF Correction See all GeneRIFs (47)

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables low voltage-gated calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables low voltage-gated calcium channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables low voltage-gated calcium channel activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables voltage-gated calcium channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables voltage-gated calcium channel activity involved SA node cell action potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables voltage-gated calcium channel activity involved in AV node cell action potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in AV node cell action potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in AV node cell to bundle of His cell signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in SA node cell action potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in SA node cell to atrial cardiac muscle cell signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within action potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in artery smooth muscle contraction ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in calcium ion import IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in calcium ion import ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in calcium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in calcium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in calcium ion transport into cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cardiac muscle cell action potential involved in contraction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chemical synaptic transmission IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in membrane depolarization during AV node cell action potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in membrane depolarization during SA node cell action potential IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in membrane depolarization during action potential IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuronal action potential IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of calcium ion-dependent exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of calcium ion-dependent exocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of atrial cardiac muscle cell membrane depolarization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of calcium ion transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of heart rate IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of heart rate by cardiac conduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of membrane potential ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within response to nickel cation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of voltage-gated calcium channel complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    voltage-dependent T-type calcium channel subunit alpha-1G

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001112813.2 → NP_001106284.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate, in-frame coding segment, compared to variant 1. The resulting protein (isoform b) is shorter when it is compared to isoform a.
      Source sequence(s)
      AJ012569, AW124914, AW457316, CF536661, DQ317412
      Consensus CDS
      CCDS48885.1
      UniProtKB/TrEMBL
      E9PWL1, Q27YN9
      Related
      ENSMUSP00000021234.9, ENSMUST00000021234.15
      Conserved Domains (1) summary
      pfam00520
      Location:760 → 975
      Ion_trans; Ion transport protein

    2. NM_001177888.1 → NP_001171359.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate, in-frame coding segment and uses a different splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform b) is shorter when it is compared to isoform a.
      Source sequence(s)
      AJ012569, AL645965, AW457316, BC057399
      Consensus CDS
      CCDS48886.1
      UniProtKB/TrEMBL
      Q27YN9, Q5SUF9
      Related
      ENSMUSP00000103419.2, ENSMUST00000107790.8
      Conserved Domains (1) summary
      pfam00520
      Location:760 → 975
      Ion_trans; Ion transport protein

    3. NM_001177890.1 → NP_001171361.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate, in-frame coding segment and uses two different splice sites in the coding region, compared to variant 1. The resulting protein (isoform d) is shorter when it is compared to isoform a.
      Source sequence(s)
      AJ012569, AK129294, AW457316, BC057399, BU708898, CF536661, CN667053
      Consensus CDS
      CCDS48884.1
      UniProtKB/TrEMBL
      Q5SUG1, Q6PFV8
      Related
      ENSMUSP00000103415.2, ENSMUST00000107786.8
      Conserved Domains (1) summary
      pfam00520
      Location:743 → 958
      Ion_trans; Ion transport protein

    4. NM_009783.3 → NP_033913.2  voltage-dependent T-type calcium channel subunit alpha-1G isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This transcript (1) represents the longest transcript and it encodes the longest protein (isoform a).
      Source sequence(s)
      AJ012569, AW124914, AW457316, CF536661, DQ317412
      Consensus CDS
      CCDS25255.1
      UniProtKB/TrEMBL
      Q5SUG4, Q9WUT2
      Related
      ENSMUSP00000098127.4, ENSMUST00000100561.10
      Conserved Domains (1) summary
      pfam00520
      Location:760 → 968
      Ion_trans; Ion transport protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      94299217..94365226 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532087.5 → XP_006532150.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X32

      UniProtKB/TrEMBL
      Q27YN9, Q5SUF8
      Related
      ENSMUSP00000103420.2, ENSMUST00000107791.8
      Conserved Domains (2) summary
      PHA03307
      Location:1972 → 2251
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 975
      Ion_trans; Ion transport protein

    2. XM_006532076.5 → XP_006532139.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X13

      UniProtKB/TrEMBL
      Q27YN9
      Conserved Domains (2) summary
      PHA03307
      Location:2065 → 2344
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 975
      Ion_trans; Ion transport protein

    3. XM_006532084.5 → XP_006532147.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X26

      UniProtKB/TrEMBL
      Q5SUF6, Q9WUT2
      Related
      ENSMUSP00000099455.3, ENSMUST00000103166.9
      Conserved Domains (2) summary
      PHA03307
      Location:2006 → 2285
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    4. XM_006532085.5 → XP_006532148.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X28

      UniProtKB/TrEMBL
      Q5SUG0, Q9WUT2
      Related
      ENSMUSP00000103422.2, ENSMUST00000107793.8
      Conserved Domains (2) summary
      PHA03307
      Location:1995 → 2274
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    5. XM_006532072.5 → XP_006532135.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X7

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2088 → 2367
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    6. XM_017314234.3 → XP_017169723.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X31

      UniProtKB/TrEMBL
      Q27YN9
      Conserved Domains (2) summary
      PHA03307
      Location:1976 → 2255
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 979
      Ion_trans; Ion transport protein

    7. XM_011248696.4 → XP_011246998.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X25

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2010 → 2289
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    8. XM_011248697.4 → XP_011246999.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X27

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1999 → 2278
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    9. XM_011248689.4 → XP_011246991.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X6

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2092 → 2371
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    10. XM_011248695.4 → XP_011246997.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X24

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2017 → 2296
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    11. XM_006532088.4 → XP_006532151.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X33

      UniProtKB/TrEMBL
      Q27YN9, Q5SUF5
      Related
      ENSMUSP00000103421.2, ENSMUST00000107792.8
      Conserved Domains (2) summary
      PHA03307
      Location:1965 → 2244
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 975
      Ion_trans; Ion transport protein

    12. XM_006532082.4 → XP_006532145.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X22

      UniProtKB/TrEMBL
      Q27YN9
      Conserved Domains (2) summary
      PHA03307
      Location:2028 → 2307
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 975
      Ion_trans; Ion transport protein

    13. XM_006532075.4 → XP_006532138.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X12

      UniProtKB/TrEMBL
      Q27YN9
      Conserved Domains (2) summary
      PHA03307
      Location:2076 → 2355
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 975
      Ion_trans; Ion transport protein

    14. XM_006532083.4 → XP_006532146.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X23

      UniProtKB/TrEMBL
      Q27YN9
      Conserved Domains (2) summary
      PHA03307
      Location:1910 → 2302
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 975
      Ion_trans; Ion transport protein

    15. XM_006532073.4 → XP_006532136.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X10

      UniProtKB/TrEMBL
      Q27YN9
      Conserved Domains (2) summary
      PHA03307
      Location:2083 → 2362
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 975
      Ion_trans; Ion transport protein

    16. XM_006532086.4 → XP_006532149.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X30

      UniProtKB/TrEMBL
      Q5SUG3, Q9WUT2
      Related
      ENSMUSP00000103417.2, ENSMUST00000107788.8
      Conserved Domains (2) summary
      PHA03307
      Location:1988 → 2267
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    17. XM_006532081.4 → XP_006532144.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X21

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1926 → 2318
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    18. XM_006532074.4 → XP_006532137.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X11

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2083 → 2360
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    19. XM_036156254.1 → XP_036012147.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X17

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2051 → 2330
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    20. XM_006532079.4 → XP_006532142.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X16

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1944 → 2336
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    21. XM_006532070.4 → XP_006532133.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X4

      UniProtKB/TrEMBL
      Q5SUF7, Q9WUT2
      Related
      ENSMUSP00000103418.2, ENSMUST00000107789.8
      Conserved Domains (2) summary
      PHA03307
      Location:2099 → 2378
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    22. XM_006532080.4 → XP_006532143.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X20

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1933 → 2325
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    23. XM_006532069.4 → XP_006532132.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X2

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2106 → 2385
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:742 → 968
      Ion_trans; Ion transport protein

    24. XM_011248690.3 → XP_011246992.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X8

      UniProtKB/TrEMBL
      Q27YN9
      Conserved Domains (2) summary
      PHA03307
      Location:2087 → 2366
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 979
      Ion_trans; Ion transport protein

    25. XM_011248698.3 → XP_011247000.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X29

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1992 → 2271
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    26. XM_011248691.3 → XP_011246993.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X9

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2087 → 2364
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    27. XM_011248687.3 → XP_011246989.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X3

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2103 → 2382
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    28. XM_030245496.1 → XP_030101356.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X19

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2044 → 2323
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    29. XM_011248694.3 → XP_011246996.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X18

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1937 → 2329
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    30. XM_011248693.3 → XP_011246995.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X15

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2062 → 2341
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    31. XM_011248692.3 → XP_011246994.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X14

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1955 → 2347
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    32. XM_011248686.3 → XP_011246988.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X1

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2110 → 2389
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    33. XM_030245497.1 → XP_030101357.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X34

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:1916 → 2193
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:550 → 776
      Ion_trans; Ion transport protein

    34. XM_011248688.3 → XP_011246990.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X5

      UniProtKB/TrEMBL
      Q9WUT2
      Conserved Domains (2) summary
      PHA03307
      Location:2093 → 2372
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:729 → 955
      Ion_trans; Ion transport protein

    35. XM_017314235.3 → XP_017169724.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X35

      UniProtKB/TrEMBL
      Q6ZPX4
      Conserved Domains (2) summary
      PHA03307
      Location:1317 → 1596
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00520
      Location:487 → 759
      Ion_trans; Ion transport protein

    36. XM_011248700.4 → XP_011247002.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X37

      Conserved Domains (1) summary
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    37. XM_011248699.4 → XP_011247001.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X36

      Conserved Domains (1) summary
      pfam00520
      Location:746 → 972
      Ion_trans; Ion transport protein

    RNA

    1. XR_388339.2 RNA Sequence

    2. XR_388338.2 RNA Sequence

    3. XR_879510.2 RNA Sequence

    4. XR_003949260.1 RNA Sequence

    5. XR_003949261.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous