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4933434E20Rik RIKEN cDNA 4933434E20 gene [ Mus musculus (house mouse) ]

Gene ID: 99650, updated on 18-Apr-2024

Summary

Official Symbol
4933434E20Rikprovided by MGI
Official Full Name
RIKEN cDNA 4933434E20 geneprovided by MGI
Primary source
MGI:MGI:1914027
See related
Ensembl:ENSMUSG00000027942 AllianceGenome:MGI:1914027
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NICE-3; NS5ATP4; 5730552F22Rik
Summary
Involved in phagocytosis. Acts upstream of or within in utero embryonic development. Predicted to be located in Golgi apparatus and mitochondrion. Orthologous to human C1orf43 (chromosome 1 open reading frame 43). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 21.0), placenta adult (RPKM 14.7) and 27 other tissues See more
Orthologs
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Genomic context

Location:
3 F1; 3 39.2 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (89958941..89969754)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90051636..90063341)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-associated protein 2-like Neighboring gene predicted gene, 24608 Neighboring gene microRNA 7669 Neighboring gene STARR-seq mESC enhancer starr_08270 Neighboring gene cilia and flagella associated protein 141 Neighboring gene microRNA 190b

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in phagocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phagocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in phagocytosis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein C1orf43 homolog
Names
uncharacterized protein C1orf43 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001287086.2NP_001274015.1  protein C1orf43 homolog isoform 3

    See identical proteins and their annotated locations for NP_001274015.1

    Status: VALIDATED

    Source sequence(s)
    AC163616
    UniProtKB/TrEMBL
    Q05D39
    Conserved Domains (1) summary
    pfam07406
    Location:261
    NICE-3; NICE-3 protein
  2. NM_001287087.2NP_001274016.1  protein C1orf43 homolog isoform 1

    See identical proteins and their annotated locations for NP_001274016.1

    Status: VALIDATED

    Source sequence(s)
    AC163616
    Consensus CDS
    CCDS17520.1
    UniProtKB/Swiss-Prot
    Q3UBD8, Q8BII4, Q8BIP7, Q8R092, Q8R240, Q9CV59, Q9CYB6
    UniProtKB/TrEMBL
    Q3UCR6
    Related
    ENSMUSP00000124554.2, ENSMUST00000159064.8
    Conserved Domains (1) summary
    pfam07406
    Location:6188
    NICE-3; NICE-3 protein
  3. NM_025762.4NP_080038.1  protein C1orf43 homolog isoform 1

    See identical proteins and their annotated locations for NP_080038.1

    Status: VALIDATED

    Source sequence(s)
    AC163616
    Consensus CDS
    CCDS17520.1
    UniProtKB/Swiss-Prot
    Q3UBD8, Q8BII4, Q8BIP7, Q8R092, Q8R240, Q9CV59, Q9CYB6
    UniProtKB/TrEMBL
    Q3UCR6
    Related
    ENSMUSP00000124028.2, ENSMUST00000160640.8
    Conserved Domains (1) summary
    pfam07406
    Location:6188
    NICE-3; NICE-3 protein
  4. NM_027500.5NP_081776.2  protein C1orf43 homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC163616
    Consensus CDS
    CCDS50967.1
    UniProtKB/Swiss-Prot
    Q8R092
    Related
    ENSMUSP00000029552.7, ENSMUST00000029552.13
    Conserved Domains (1) summary
    pfam07406
    Location:6188
    NICE-3; NICE-3 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    89958941..89969754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)