Format

Send to:

Choose Destination

FAM20B FAM20B glycosaminoglycan xylosylkinase [ Homo sapiens (human) ]

Gene ID: 9917, updated on 21-Dec-2019

Summary

Official Symbol
FAM20Bprovided by HGNC
Official Full Name
FAM20B glycosaminoglycan xylosylkinaseprovided by HGNC
Primary source
HGNC:HGNC:23017
See related
Ensembl:ENSG00000116199 MIM:611063
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
gxk1
Expression
Ubiquitous expression in adrenal (RPKM 13.7), brain (RPKM 12.6) and 25 other tissues See more
Orthologs

Genomic context

See FAM20B in Genome Data Viewer
Location:
1q25.2
Exon count:
11
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (179025804..179076574)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (178994939..179045702)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102724754 Neighboring gene CRISPRi-validated cis-regulatory element chr1.10033 Neighboring gene ribosomal protein S26 pseudogene 16 Neighboring gene torsin family 3 member A Neighboring gene ABL proto-oncogene 2, non-receptor tyrosine kinase Neighboring gene SET pseudogene 10

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphotransferase activity, alcohol group as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphotransferase activity, alcohol group as acceptor IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
NOT protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
glycosaminoglycan xylosylkinase
Names
family with sequence similarity 20, member B
xylose kinase
NP_001311239.1
NP_001311240.1
NP_055679.1
XP_016858490.1
XP_016858491.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001324310.1NP_001311239.1  glycosaminoglycan xylosylkinase

    Status: VALIDATED

    Source sequence(s)
    AL139132
    Consensus CDS
    CCDS1328.1
    UniProtKB/Swiss-Prot
    O75063
    UniProtKB/TrEMBL
    A0A024R918
    Conserved Domains (1) summary
    cd10470
    Location:188394
    FAM20B_C; C-terminal putative kinase domain of FAM20B xylose kinase
  2. NM_001324311.1NP_001311240.1  glycosaminoglycan xylosylkinase

    Status: VALIDATED

    Source sequence(s)
    AL139132
    Consensus CDS
    CCDS1328.1
    UniProtKB/Swiss-Prot
    O75063
    UniProtKB/TrEMBL
    A0A024R918
    Conserved Domains (1) summary
    cd10470
    Location:188394
    FAM20B_C; C-terminal putative kinase domain of FAM20B xylose kinase
  3. NM_014864.4NP_055679.1  glycosaminoglycan xylosylkinase

    See identical proteins and their annotated locations for NP_055679.1

    Status: VALIDATED

    Source sequence(s)
    AL139132, BC051794, CA844342
    Consensus CDS
    CCDS1328.1
    UniProtKB/Swiss-Prot
    O75063
    UniProtKB/TrEMBL
    A0A024R918
    Related
    ENSP00000263733.4, ENST00000263733.5
    Conserved Domains (1) summary
    cd10470
    Location:188394
    FAM20B_C; C-terminal putative kinase domain of FAM20B xylose kinase

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    179025804..179076574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003001.2XP_016858490.1  glycosaminoglycan xylosylkinase isoform X1

  2. XM_017003002.1XP_016858491.1  glycosaminoglycan xylosylkinase isoform X1

RNA

  1. XR_002958229.1 RNA Sequence

Support Center