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ZBED4 zinc finger BED-type containing 4 [ Homo sapiens (human) ]

Gene ID: 9889, updated on 1-Jun-2020

Summary

Official Symbol
ZBED4provided by HGNC
Official Full Name
zinc finger BED-type containing 4provided by HGNC
Primary source
HGNC:HGNC:20721
See related
Ensembl:ENSG00000100426 MIM:612552
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in bone marrow (RPKM 4.8), colon (RPKM 4.3) and 25 other tissues See more
Orthologs

Genomic context

See ZBED4 in Genome Data Viewer
Location:
22q13.33
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (49853844..49890080)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (50247497..50283726)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene bromodomain containing 1 Neighboring gene suppressor of cytokine signaling 2 pseudogene Neighboring gene uncharacterized LOC105377205 Neighboring gene atherin-like Neighboring gene ALG12 alpha-1,6-mannosyltransferase Neighboring gene uncharacterized LOC107985553 Neighboring gene cysteine rich with EGF like domains 2 Neighboring gene microRNA 6821 Neighboring gene Pim-3 proto-oncogene, serine/threonine kinase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISM
Inferred from Sequence Model
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger BED domain-containing protein 4
Names
zinc finger, BED domain containing 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014838.3NP_055653.2  zinc finger BED domain-containing protein 4

    See identical proteins and their annotated locations for NP_055653.2

    Status: VALIDATED

    Source sequence(s)
    AA809789, AL117328, DB457646
    Consensus CDS
    CCDS33677.1
    UniProtKB/Swiss-Prot
    O75132
    Related
    ENSP00000216268.4, ENST00000216268.6
    Conserved Domains (2) summary
    pfam02892
    Location:118166
    zf-BED; BED zinc finger
    pfam05699
    Location:10881164
    Dimer_Tnp_hAT; hAT family C-terminal dimerisation region

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    49853844..49890080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024452312.1XP_024308080.1  zinc finger BED domain-containing protein 4 isoform X1

    Conserved Domains (2) summary
    pfam02892
    Location:118166
    zf-BED; BED zinc finger
    pfam05699
    Location:10881164
    Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
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