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TATDN2 TatD DNase domain containing 2 [ Homo sapiens (human) ]

Gene ID: 9797, updated on 8-Jul-2021

Summary

Official Symbol
TATDN2provided by HGNC
Official Full Name
TatD DNase domain containing 2provided by HGNC
Primary source
HGNC:HGNC:28988
See related
Ensembl:ENSG00000157014 MIM:619330
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in bone marrow (RPKM 17.8), lymph node (RPKM 17.6) and 25 other tissues See more
Orthologs
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Genomic context

See TATDN2 in Genome Data Viewer
Location:
3p25.3
Exon count:
8
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (10248459..10281218)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (10290143..10322902)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene 3p25 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Alu-mediated recombination region Neighboring gene 3p25 IRAK2 Alu-mediated recombination region Neighboring gene von Hippel-Lindau tumor suppressor Neighboring gene interleukin 1 receptor associated kinase 2 Neighboring gene 3p25 TatD DNase domain containing 2 Alu-mediated recombination region Neighboring gene microRNA 12127 Neighboring gene Sharpr-MPRA regulatory region 4342 Neighboring gene long intergenic non-protein coding RNA 852 Neighboring gene ghrelin opposite strand/antisense RNA Neighboring gene ghrelin and obestatin prepropeptide

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0218, MGC126819, MGC126825

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in nucleic acid phosphodiester bond hydrolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
putative deoxyribonuclease TATDN2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014760.4NP_055575.3  putative deoxyribonuclease TATDN2

    See identical proteins and their annotated locations for NP_055575.3

    Status: VALIDATED

    Source sequence(s)
    AC022384, AW274827, BC090935, BC101776, BG674405, BP249277
    Consensus CDS
    CCDS33698.1
    UniProtKB/Swiss-Prot
    Q93075
    UniProtKB/TrEMBL
    A0A024R2F3
    Related
    ENSP00000408736.2, ENST00000448281.7
    Conserved Domains (1) summary
    pfam01026
    Location:496760
    TatD_DNase; TatD related DNase

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    10248459..10281218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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