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GPRIN2 G protein regulated inducer of neurite outgrowth 2 [ Homo sapiens (human) ]

Gene ID: 9721, updated on 6-Nov-2022

Summary

Official Symbol
GPRIN2provided by HGNC
Official Full Name
G protein regulated inducer of neurite outgrowth 2provided by HGNC
Primary source
HGNC:HGNC:23730
See related
Ensembl:ENSG00000204175 MIM:611240; AllianceGenome:HGNC:23730
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GRIN2; KIAA0514
Summary
Predicted to be involved in neuron projection development. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: suggests misassembly
Expression
Biased expression in lung (RPKM 5.6), skin (RPKM 4.9) and 12 other tissues See more
Orthologs
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Genomic context

See GPRIN2 in Genome Data Viewer
Location:
10q11.22
Exon count:
9
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (46541736..46557596, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (47428090..47443951, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (46992021..47007881)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 842 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 33 Neighboring gene neuropeptide Y receptor Y4 Neighboring gene uncharacterized LOC124902419 Neighboring gene Sharpr-MPRA regulatory regions 2784 and 8617 duplicate 1 Neighboring gene SYT15 antisense RNA 1 Neighboring gene synaptotagmin 15 Neighboring gene uncharacterized LOC105378289 Neighboring gene shieldin complex subunit 2 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC15171

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
G protein-regulated inducer of neurite outgrowth 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001385275.1NP_001372204.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  2. NM_001385276.1NP_001372205.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  3. NM_001385277.1NP_001372206.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  4. NM_001385278.1NP_001372207.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Related
    ENSP00000363436.1, ENST00000374317.2
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  5. NM_001385279.1NP_001372208.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  6. NM_001385280.1NP_001372209.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  7. NM_001385281.1NP_001372210.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  8. NM_001385282.1NP_001372211.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Related
    ENSP00000363433.4, ENST00000374314.6
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  9. NM_001385283.1NP_001372212.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  10. NM_001385287.1NP_001372216.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  11. NM_001385289.1NP_001372218.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  12. NM_001385291.1NP_001372220.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  13. NM_001385293.1NP_001372222.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  14. NM_001385294.1NP_001372223.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  15. NM_001385295.1NP_001372224.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  16. NM_001385296.1NP_001372225.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  17. NM_001385297.1NP_001372226.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  18. NM_001385298.1NP_001372227.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  19. NM_001385299.1NP_001372228.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  20. NM_001385300.1NP_001372229.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  21. NM_001385301.1NP_001372230.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  22. NM_001394739.1NP_001381668.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  23. NM_001394740.1NP_001381669.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  24. NM_001394741.1NP_001381670.1  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  25. NM_001394742.1NP_001381671.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  26. NM_001394743.1NP_001381672.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  27. NM_001394744.1NP_001381673.1  G protein-regulated inducer of neurite outgrowth 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  28. NM_014696.5NP_055511.2  G protein-regulated inducer of neurite outgrowth 2 isoform 1

    See identical proteins and their annotated locations for NP_055511.2

    Status: VALIDATED

    Source sequence(s)
    AL356056, AL645529, AL732434
    Consensus CDS
    CCDS73101.1
    UniProtKB/Swiss-Prot
    O60269, Q5SVF0
    Conserved Domains (1) summary
    pfam15235
    Location:349450
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    46541736..46557596 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017016981.3XP_016872470.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  2. XM_017016982.3XP_016872471.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  3. XM_017016974.3XP_016872463.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  4. XM_017016984.3XP_016872473.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  5. XM_017016983.3XP_016872472.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  6. XM_017016976.3XP_016872465.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  7. XM_017016977.3XP_016872466.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  8. XM_017016975.3XP_016872464.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
  9. XM_017016978.3XP_016872467.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    Conserved Domains (1) summary
    pfam15235
    Location:373474
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    47428090..47443951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)