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SEC14L5 SEC14 like lipid binding 5 [ Homo sapiens (human) ]

Gene ID: 9717, updated on 5-Aug-2022

Summary

Official Symbol
SEC14L5provided by HGNC
Official Full Name
SEC14 like lipid binding 5provided by HGNC
Primary source
HGNC:HGNC:29032
See related
Ensembl:ENSG00000103184 MIM:619412; AllianceGenome:HGNC:29032
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRELID4B
Expression
Biased expression in brain (RPKM 6.8), heart (RPKM 1.4) and 3 other tissues See more
Orthologs
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Genomic context

See SEC14L5 in Genome Data Viewer
Location:
16p13.3
Exon count:
16
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (4958330..5019157)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (4987865..5048658)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (5008331..5069158)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903637 Neighboring gene periplakin Neighboring gene uncharacterized LOC105371064 Neighboring gene NAGPA antisense RNA 1 Neighboring gene N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Neighboring gene chromosome 16 open reading frame 89

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0420

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
SEC14-like protein 5
Names
SEC14-like 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014692.2NP_055507.1  SEC14-like protein 5

    See identical proteins and their annotated locations for NP_055507.1

    Status: VALIDATED

    Source sequence(s)
    AB007880, AC007011, AC026458
    Consensus CDS
    CCDS45403.1
    UniProtKB/Swiss-Prot
    O43304
    Related
    ENSP00000251170.6, ENST00000251170.12
    Conserved Domains (3) summary
    smart00516
    Location:306479
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    smart01100
    Location:243288
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam04707
    Location:17173
    PRELI; PRELI-like family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    4958330..5019157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450497.2XP_024306265.1  SEC14-like protein 5 isoform X1

    UniProtKB/Swiss-Prot
    O43304
    Conserved Domains (3) summary
    smart00516
    Location:306479
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    smart01100
    Location:243288
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam04707
    Location:17173
    PRELI; PRELI-like family
  2. XM_024450498.2XP_024306266.1  SEC14-like protein 5 isoform X1

    UniProtKB/Swiss-Prot
    O43304
    Conserved Domains (3) summary
    smart00516
    Location:306479
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    smart01100
    Location:243288
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam04707
    Location:17173
    PRELI; PRELI-like family

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    4987865..5048658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)