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TTI1 TELO2 interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 9675, updated on 1-Jun-2020

Summary

Official Symbol
TTI1provided by HGNC
Official Full Name
TELO2 interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:29029
See related
Ensembl:ENSG00000101407 MIM:614425
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
smg-10; KIAA0406
Expression
Ubiquitous expression in testis (RPKM 7.8), thyroid (RPKM 6.4) and 25 other tissues See more
Orthologs

Genomic context

See TTI1 in Genome Data Viewer
Location:
20q11.23
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (37983014..38033461, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (36611419..36661870, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene V-set and transmembrane domain containing 2 like Neighboring gene RN7SK pseudogene 185 Neighboring gene regulation of nuclear pre-mRNA domain containing 1B Neighboring gene RNA, 7SL, cytoplasmic 237, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38132, KIAA0406

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of TOR signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of TOR signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
ASTRA complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
TORC1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
TORC1 complex IDA
Inferred from Direct Assay
more info
PubMed 
TORC2 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
TORC2 complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
TELO2-interacting protein 1 homolog
Names
TEL2-interacting protein 1 homolog
Tel two interacting protein 1
smg-10 homolog, nonsense mediated mRNA decay factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001303457.2NP_001290386.1  TELO2-interacting protein 1 homolog

    See identical proteins and their annotated locations for NP_001290386.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    BC013755, BU684997, DA652320
    Consensus CDS
    CCDS13300.1
    UniProtKB/Swiss-Prot
    O43156
    Related
    ENSP00000362546.3, ENST00000373447.8
  2. NM_014657.3NP_055472.1  TELO2-interacting protein 1 homolog

    See identical proteins and their annotated locations for NP_055472.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    BC013121, BU684997, DA652320
    Consensus CDS
    CCDS13300.1
    UniProtKB/Swiss-Prot
    O43156
    Related
    ENSP00000362547.2, ENST00000373448.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    37983014..38033461 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017028148.2XP_016883637.1  TELO2-interacting protein 1 homolog isoform X1

  2. XM_011529114.2XP_011527416.1  TELO2-interacting protein 1 homolog isoform X2

    See identical proteins and their annotated locations for XP_011527416.1

RNA

  1. XR_001754441.2 RNA Sequence

  2. XR_244159.4 RNA Sequence

  3. XR_001754443.2 RNA Sequence

  4. XR_001754442.2 RNA Sequence

  5. XR_936662.3 RNA Sequence

  6. XR_001754440.2 RNA Sequence

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