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SNCAIP synuclein alpha interacting protein [ Homo sapiens (human) ]

Gene ID: 9627, updated on 13-Mar-2020

Summary

Official Symbol
SNCAIPprovided by HGNC
Official Full Name
synuclein alpha interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:11139
See related
Ensembl:ENSG00000064692 MIM:603779
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Sph1; SYPH1
Summary
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Expression
Biased expression in ovary (RPKM 8.3), endometrium (RPKM 6.2) and 11 other tissues See more
Orthologs

Genomic context

See SNCAIP in Genome Data Viewer
Location:
5q23.2
Exon count:
22
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (122311354..122464219)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (121647455..121799794)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene serum response factor binding protein 1 Neighboring gene ZNF474 antisense RNA 1 Neighboring gene zinc finger protein 474-like Neighboring gene lysyl oxidase Neighboring gene zinc finger protein 474 Neighboring gene ancient vomeronasal 1 receptor pseudogene Neighboring gene uncharacterized LOC107986446 Neighboring gene uncharacterized LOC153163 Neighboring gene uncharacterized LOC105379151 Neighboring gene uncharacterized LOC101927357

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC39814

Gene Ontology Provided by GOA

Function Evidence Code Pubs
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ubiquitin protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell death IDA
Inferred from Direct Assay
more info
PubMed 
cellular protein metabolic process TAS
Traceable Author Statement
more info
 
dopamine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
regulation of inclusion body assembly IDA
Inferred from Direct Assay
more info
PubMed 
regulation of neurotransmitter secretion IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic ribonucleoprotein granule IDA
Inferred from Direct Assay
more info
 
cytosol TAS
Traceable Author Statement
more info
 
neuronal cell body NAS
Non-traceable Author Statement
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
presynaptic membrane NAS
Non-traceable Author Statement
more info
PubMed 
synaptic vesicle TAS
Traceable Author Statement
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_011486.2 RefSeqGene

    Range
    5113..157095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001242935.2NP_001229864.1  synphilin-1 isoform 1A

    See identical proteins and their annotated locations for NP_001229864.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1A) differs in the 5' UTR, lacks an alternate exon in the 5' coding region that results in translation initiation from a downstream start codon in a different reading frame, and lacks two alternate exons in the central coding region, compared to variant 2. The encoded isoform (1A) has a distinct N-terminus and is shorter than isoform 2.
    Source sequence(s)
    AI702863, BC040552, DQ227317, N21998
    Consensus CDS
    CCDS58964.1
    UniProtKB/Swiss-Prot
    Q9Y6H5
    Related
    ENSP00000368854.3, ENST00000379538.7
    Conserved Domains (4) summary
    cd00204
    Location:28144
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:28121
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:146189
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:5688
    ANK; ANK repeat [structural motif]
  2. NM_001308100.2NP_001295029.1  synphilin-1 isoform 2

    See identical proteins and their annotated locations for NP_001295029.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2).
    Source sequence(s)
    AF076929, BC040552, N21998
    Consensus CDS
    CCDS78054.1
    UniProtKB/Swiss-Prot
    Q9Y6H5
    Related
    ENSP00000261367.7, ENST00000261367.11
    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  3. NM_001308105.1NP_001295034.1  synphilin-1 isoform B

    Status: REVIEWED

    Description
    Transcript Variant: This variant (b) lacks an alternate in-frame exon in both the 5' and central coding regions, and also lacks an alternate exon that results in a frameshift in the 3' coding region, compared to variant 2. The encoded isoform (B) has a distinct C-terminus and is shorter than isoform 2. This variant lacks 5'-complete transcript support and thus its 5' UTR is incomplete.
    Source sequence(s)
    AB110789, AK299687, AK304646, AK310835, BC040552, N21998
    UniProtKB/Swiss-Prot
    Q9Y6H5
    UniProtKB/TrEMBL
    B7Z616, B7Z995
    Related
    ENSP00000422106.2, ENST00000509154.6
    Conserved Domains (4) summary
    cd00204
    Location:335450
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:335427
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:452495
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:362394
    ANK; ANK repeat [structural motif]
  4. NM_001308106.1NP_001295035.1  synphilin-1 isoform D

    Status: REVIEWED

    Description
    Transcript Variant: This variant (d) lacks two alternate exons in the 5' coding region that result in translation initiation from a downstream start codon in a different reading frame, and it also lacks an alternate exon that results in a frameshift in the 3' coding region, compared to variant 2. The encoded isoform (D) has distinct N- and C-termini and is shorter than isoform 2. This variant lacks 5'-complete transcript support and thus its 5' UTR is incomplete.
    Source sequence(s)
    AB110791, AK299687, AK304646, BC040552, N21998
    UniProtKB/Swiss-Prot
    Q9Y6H5
    UniProtKB/TrEMBL
    B7Z616, B7Z995, Q6L983
    Conserved Domains (4) summary
    cd00204
    Location:26142
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:26119
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:144187
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:5486
    ANK; ANK repeat [structural motif]
  5. NM_001308107.2NP_001295036.1  synphilin-1 isoform E

    Status: REVIEWED

    Description
    Transcript Variant: This variant (e) differs in the 5' UTR, lacks an alternate exon in the 5' coding region that results in translation initiation from a downstream start codon in a different reading frame, lacks two alternate exons in the central coding region, and also lacks an alternate exon that results in a frameshift in the 3' coding region, compared to variant 2. The encoded isoform (E) has distinct N- and C-termini and is shorter than isoform 2.
    Source sequence(s)
    AI702863, AK304646, BC033743, BC040552, N21998
    UniProtKB/Swiss-Prot
    Q9Y6H5
    UniProtKB/TrEMBL
    B7Z995
    Conserved Domains (4) summary
    cd00204
    Location:28144
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:28121
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:146189
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:5688
    ANK; ANK repeat [structural motif]
  6. NM_001308108.1NP_001295037.1  synphilin-1 isoform F

    Status: REVIEWED

    Description
    Transcript Variant: This variant (f) lacks an alternate exon in the 5' coding region that results in translation initiation from a downstream start codon in a different reading frame, lacks an alternate exon in the central coding region, and also lacks an alternate exon that results in a frameshift in the 3' coding region, compared to variant 2. The encoded isoform (F) has distinct N- and C-termini and is shorter than isoform 2. This variant lacks 5'-complete transcript support and thus its 5' UTR is incomplete.
    Source sequence(s)
    AB110793, AK299687, AK304646, BC040552, N21998
    UniProtKB/Swiss-Prot
    Q9Y6H5
    UniProtKB/TrEMBL
    B7Z616, B7Z995, Q6L981
    Conserved Domains (5) summary
    cd00204
    Location:39204
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:85181
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:4499
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:206249
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:4376
    ANK; ANK repeat [structural motif]
  7. NM_001308109.2NP_001295038.1  synphilin-1 isoform G

    Status: REVIEWED

    Description
    Transcript Variant: This variant (g) differs in the 5' UTR, lacks an alternate exon in the 5' coding region that results in translation initiation from a downstream start codon in a different reading frame, lacks three alternate exons in the central coding region, and also lacks an alternate exon that results in a frameshift in the 3' coding region, compared to variant 2. The encoded isoform (G) has distinct N- and C-termini and is shorter than isoform 2.
    Source sequence(s)
    AK304646, BC040552, N21998
    UniProtKB/Swiss-Prot
    Q9Y6H5
    UniProtKB/TrEMBL
    B7Z995
    Conserved Domains (4) summary
    cd00204
    Location:25106
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:53106
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:108151
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:5283
    ANK; ANK repeat [structural motif]
  8. NM_005460.4NP_005451.2  synphilin-1 isoform 1

    See identical proteins and their annotated locations for NP_005451.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1, also known as variant a) differs in the 5' UTR, lacks an alternate in-frame exon in the 5' coding region, and lacks an exon that results in a frameshift in the 3' coding region, compared to variant 2. The encoded isoform (1) has a distinct C-terminus and is shorter than isoform 2.
    Source sequence(s)
    AF076929, AI702863, BC040552, N21998
    Consensus CDS
    CCDS4131.1
    UniProtKB/Swiss-Prot
    Q9Y6H5
    Related
    ENSP00000261368.8, ENST00000261368.13
    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain

RNA

  1. NR_131761.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (c) includes two additional exons in the central region but lacks an alternate exon in the 3' region, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). This variant lacks 5'-complete transcript support and thus its 5' end is incomplete.
    Source sequence(s)
    AB110790, AK299687, AK304646, BC040552, N21998
    Related
    ENST00000395469.6
  2. NR_131762.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) contains an alternate 5' terminal exon, and lacks five internal exons but includes an additional internal exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK299687, AK304646, BC040552, N21998
    Related
    ENST00000510658.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    122311354..122464219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006714734.2XP_006714797.1  synphilin-1 isoform X4

    See identical proteins and their annotated locations for XP_006714797.1

    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  2. XM_011543738.2XP_011542040.1  synphilin-1 isoform X1

    See identical proteins and their annotated locations for XP_011542040.1

    UniProtKB/Swiss-Prot
    Q9Y6H5
    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  3. XM_017010083.1XP_016865572.1  synphilin-1 isoform X7

    Conserved Domains (4) summary
    cd00204
    Location:34150
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:34127
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:152195
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:6294
    ANK; ANK repeat [structural motif]
  4. XM_024446269.1XP_024302037.1  synphilin-1 isoform X10

    Conserved Domains (3) summary
    cd00204
    Location:34150
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:6294
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:152195
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  5. XM_024446266.1XP_024302034.1  synphilin-1 isoform X4

    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  6. XM_024446268.1XP_024302036.1  synphilin-1 isoform X6

    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  7. XM_024446267.1XP_024302035.1  synphilin-1 isoform X6

    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  8. XM_011543739.1XP_011542041.1  synphilin-1 isoform X1

    See identical proteins and their annotated locations for XP_011542041.1

    UniProtKB/Swiss-Prot
    Q9Y6H5
    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  9. XM_005272139.1XP_005272196.1  synphilin-1 isoform X4

    See identical proteins and their annotated locations for XP_005272196.1

    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  10. XM_017010085.1XP_016865574.1  synphilin-1 isoform X11

    Conserved Domains (4) summary
    cd00204
    Location:26142
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:26119
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:144187
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:5486
    ANK; ANK repeat [structural motif]
  11. XM_017010084.1XP_016865573.1  synphilin-1 isoform X9

  12. XM_017010086.1XP_016865575.1  synphilin-1 isoform X12

  13. XM_011543737.2XP_011542039.1  synphilin-1 isoform X1

    See identical proteins and their annotated locations for XP_011542039.1

    UniProtKB/Swiss-Prot
    Q9Y6H5
    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  14. XM_017010079.1XP_016865568.1  synphilin-1 isoform X2

  15. XM_017010080.1XP_016865569.1  synphilin-1 isoform X3

    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  16. XM_017010081.1XP_016865570.1  synphilin-1 isoform X5

    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  17. XM_005272138.4XP_005272195.1  synphilin-1 isoform X4

    See identical proteins and their annotated locations for XP_005272195.1

    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  18. XM_011543743.2XP_011542045.1  synphilin-1 isoform X1

    See identical proteins and their annotated locations for XP_011542045.1

    UniProtKB/Swiss-Prot
    Q9Y6H5
    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  19. XM_011543749.2XP_011542051.1  synphilin-1 isoform X7

    Conserved Domains (4) summary
    cd00204
    Location:34150
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:34127
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:152195
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:6294
    ANK; ANK repeat [structural motif]
  20. XM_011543745.1XP_011542047.1  synphilin-1 isoform X4

    See identical proteins and their annotated locations for XP_011542047.1

    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  21. XM_017010082.1XP_016865571.1  synphilin-1 isoform X6

    UniProtKB/Swiss-Prot
    Q9Y6H5
    Conserved Domains (3) summary
    cd00204
    Location:345510
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:349382
    ANK; ANK repeat [structural motif]
    pfam16700
    Location:512555
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
  22. XM_011543741.2XP_011542043.1  synphilin-1 isoform X1

    See identical proteins and their annotated locations for XP_011542043.1

    UniProtKB/Swiss-Prot
    Q9Y6H5
    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  23. XM_017010078.1XP_016865567.1  synphilin-1 isoform X1

    UniProtKB/Swiss-Prot
    Q9Y6H5
    Conserved Domains (5) summary
    cd00204
    Location:392557
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:438534
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:397452
    Ank_4; Ankyrin repeats (many copies)
    pfam16700
    Location:559602
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:396429
    ANK; ANK repeat [structural motif]
  24. XM_011543750.1XP_011542052.1  synphilin-1 isoform X8

    Conserved Domains (4) summary
    cd00204
    Location:26142
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:26119
    Ank_2; Ankyrin repeats (3 copies)
    pfam16700
    Location:144187
    SNCAIP_SNCA_bd; Synphilin-1 alpha-Synuclein-binding domain
    sd00045
    Location:5486
    ANK; ANK repeat [structural motif]

RNA

  1. XR_001742362.1 RNA Sequence

  2. XR_001742363.1 RNA Sequence

  3. XR_001742364.1 RNA Sequence

  4. XR_001742365.2 RNA Sequence

  5. XR_001742366.1 RNA Sequence

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