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fimB Type 1 fimbriae regulatory protein FimB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948832, updated on 4-Apr-2024

Summary

Gene symbol
fimB
Gene description
Type 1 fimbriae regulatory protein FimB
Primary source
ASAP:ABE-0014141
Locus tag
b4312
See related
ECOCYC:EG10309
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4303; pil
Summary
FimB, along with FimE, is a recombinase in Escherichia coli which catalyzes the site-specific recombination required for inversion of a 314-bp invertible DNA element, the fim switch (fimS), to control transcription of the type I fimbrial structural genes--a process known as phase-variation switching. fimS contains the promoter for expression of the fimbrial structural genes. [More information is available at EcoCyc: EG10309].
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Genomic context

Sequence:
NC_000913.3 (4540957..4541559)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene N-acetylneuraminate mutarotase Neighboring gene N-acetylneuraminate outer membrane channel Neighboring gene regulator for fimA Neighboring gene type 1 fimbriae major subunit

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in DNA integration IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within DNA integration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within DNA recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
Type 1 fimbriae regulatory protein FimB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4540957..4541559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418732.1 Type 1 fimbriae regulatory protein FimB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418732.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A4Y6GMQ3, A0A4Y6GMV7, A0A5B9AMW1
    Conserved Domains (1) summary
    PRK09870
    Location:1200
    PRK09870; tyrosine recombinase; Provisional