U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nrdG anaerobic ribonucleoside-triphosphate reductase activating protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948757, updated on 23-Nov-2023

Summary

Gene symbol
nrdG
Gene description
anaerobic ribonucleoside-triphosphate reductase activating protein
Primary source
ASAP:ABE-0013860
Locus tag
b4237
See related
ECOCYC:G812
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4232; yjgE
Summary
FNR regulon. [More information is available at EcoGene: EG12523]. An nrdG null mutant does not grow under entirely anaerobic conditions, but grows under aerobic or microaerophilic conditions due to the activity of NrdA and/or NrdB . [More information is available at EcoCyc: G812].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (4459900..4460364, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene metalloprotease subunit TldE Neighboring gene pseudo Neighboring gene anaerobic ribonucleoside-triphosphate reductase Neighboring gene trehalose-6-phosphate hydrolase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables [formate-C-acetyltransferase]-activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables iron-sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of anaerobic ribonucleoside-triphosphate reductase complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
anaerobic ribonucleoside-triphosphate reductase activating protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4459900..4460364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418658.1 anaerobic ribonucleoside-triphosphate reductase activating protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418658.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827XT09
    Conserved Domains (1) summary
    PRK11121
    Location:1154
    nrdG; anaerobic ribonucleoside-triphosphate reductase-activating protein