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aceA isocitrate lyase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948517, updated on 4-Feb-2024

Summary

Gene symbol
aceA
Gene description
isocitrate lyase
Primary source
ASAP:ABE-0013128
Locus tag
b4015
See related
ECOCYC:EG10022
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4007; icl
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Genomic context

Sequence:
NC_000913.3 (4217109..4218413)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene homoserine O-succinyltransferase Neighboring gene malate synthase A Neighboring gene ncRNA Neighboring gene isocitrate dehydrogenase kinase/phosphatase Neighboring gene regulator of acetyl CoA synthetase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables cation binding IDA
Inferred from Direct Assay
more info
PubMed 
enables isocitrate lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables isocitrate lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables isocitrate lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within glyoxylate cycle IC
Inferred by Curator
more info
PubMed 
involved_in glyoxylate cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 

General protein information

Preferred Names
isocitrate lyase
NP_418439.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4217109..4218413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418439.1 isocitrate lyase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418439.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8H9MNK4
    Conserved Domains (1) summary
    PRK15063
    Location:1434
    PRK15063; isocitrate lyase; Provisional