U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

argB acetylglutamate kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948464, updated on 8-Apr-2026
Official Symbol
argB
Official Full Name
acetylglutamate kinase
Primary source
ECOCYC:EG10064
Locus tag
b3959
See related
ASAP:ABE-0012967
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3950
Summary
Acetylglutamate kinase (ArgB) catalyzes the second step in ornithine and arginine biosynthesis. [More information is available at EcoCyc: EG10064].
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (4156013..4156789)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene acetylornithine deacetylase Neighboring gene N-acetylglutamylphosphate reductase Neighboring gene argininosuccinate lyase Neighboring gene ncRNA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables acetylglutamate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acetylglutamate kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables acetylglutamate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in L-arginine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-arginine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in L-arginine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
acetylglutamate kinase
NP_418394.3

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4156013..4156789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418394.3 acetylglutamate kinase

    See identical proteins and their annotated locations for NP_418394.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A377E064, A0A8T5ZAM0
    Conserved Domains (1) summary
    cd04249
    Location:5 → 256
    AAK_NAGK-NC; N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of ornithine ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.