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argE acetylornithine deacetylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948456, updated on 6-Jul-2026
Official Symbol
argE
Official Full Name
acetylornithine deacetylase
Primary source
ECOCYC:EG11286
Locus tag
b3957
See related
ASAP:ABE-0012955
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3948
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Sequence:
NC_000913.3 (4153696..4154847, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoethanolamine transferase EptC Neighboring gene phosphoenolpyruvate carboxylase Neighboring gene N-acetylglutamylphosphate reductase Neighboring gene acetylglutamate kinase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural characterization of Zn(II)-, Co(II)-, and Mn(II)-loaded forms of the argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coli. Tao Y, et al. J Inorg Biochem, 2012 Jun. PMID 22459917, Free PMC Article
  2. Mechanistic analysis of the argE-encoded N-acetylornithine deacetylase. Javid-Majd F, et al. Biochemistry, 2000 Feb 15. PMID 10684608
  3. argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coli contains a dinuclear metalloactive site. McGregor WC, et al. J Am Chem Soc, 2005 Oct 12. PMID 16201833
  4. Selection for genetically repressible (ArgR+) strains of Escherichia coli K12 from genetically derepressed (ArgR-) mutants using acetylnorvaline. Kelker NE, et al. Mol Gen Genet, 1974. PMID 4607756
  5. Acetylornithine deacetylase, succinyldiaminopimelate desuccinylase and carboxypeptidase G2 are evolutionarily related. Boyen A, et al. Gene, 1992 Jul 1. PMID 1628835

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest the Zn(II), Co(II), and Mn(II) bind to N-acetyl-l-ornithine deacetylase (ArgE) in a cooperative manner.
    Title: Structural characterization of Zn(II)-, Co(II)-, and Mn(II)-loaded forms of the argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coli.
  2. Data show that most N-acety-L-ornithine deacetylase(NAOase) was expressed as inclusion bodies.
    Title: [Studies on the expression, purification and renaturation of recombinant N-acety-L-ornithine deacetylase].
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables acetylornithine deacetylase activity EXP
Inferred from Experiment
more info
 PubMed 
enables acetylornithine deacetylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acetylornithine deacetylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables acetylornithine deacetylase activity IEA
Inferred from Electronic Annotation
more info
  
enables cobalt ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables deacetylase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-arginine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-arginine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in L-arginine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
acetylornithine deacetylase
NP_418392.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4153696..4154847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418392.1 acetylornithine deacetylase

    See identical proteins and their annotated locations for NP_418392.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0H2Z5S0
    Conserved Domains (1) summary
    PRK05111
    Location:2 → 383
    PRK05111; acetylornithine deacetylase; Provisional
Nucleotide Protein
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