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waaS lipopolysaccharide core biosynthesis protein WaaS [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948151, updated on 30-Jul-2025
Official Symbol
waaS
Official Full Name
lipopolysaccharide core biosynthesis protein WaaS
Primary source
ECOCYC:EG11350
Locus tag
b3629
See related
ASAP:ABE-0011864
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3619; rfaS
Summary
The lipopolysaccharide of Escherichia coli K-12 consists of two major components: the hydrophobic lipid A moiety inserted into the outer membrane and the phosphorylated core oligosaccharide . [More information is available at EcoCyc: EG11350].
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Sequence:
NC_000913.3 (3804181..3805116, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-D-glucose:(glucosyl)LPS alpha-1,3-glucosyltransferase Neighboring gene UDP-D-galactose:(glucosyl)lipopolysaccharide-1,6-D-galactosyltransferase Neighboring gene lipopolysaccharide core heptose (I) kinase Neighboring gene lipopolysaccharide glucosyltransferase I Neighboring gene lipopolysaccharide core heptosyltransferase 3

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The rfaS gene, which is involved in production of a rough form of lipopolysaccharide core in Escherichia coli K-12, is not present in the rfa cluster of Salmonella typhimurium LT2. Klena JD, et al. J Bacteriol, 1993 Mar. PMID 8444813, Free PMC Article
  2. Genes for TDP-rhamnose synthesis affect the pattern of lipopolysaccharide heterogeneity in Escherichia coli K-12. Klena JD, et al. J Bacteriol, 1994 Jul. PMID 7517388, Free PMC Article
  3. Genetic analysis of lipopolysaccharide core biosynthesis by Escherichia coli K-12: insertion mutagenesis of the rfa locus. Austin EA, et al. J Bacteriol, 1990 Sep. PMID 2168379, Free PMC Article
  4. Genetic analysis of the genes involved in synthesis of the lipopolysaccharide core in Escherichia coli K-12: three operons in the rfa locus. Roncero C, et al. J Bacteriol, 1992 May. PMID 1577693, Free PMC Article
  5. Role of the rfaG and rfaP genes in determining the lipopolysaccharide core structure and cell surface properties of Escherichia coli K-12. Parker CT, et al. J Bacteriol, 1992 Apr. PMID 1348243, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in lipopolysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipopolysaccharide core region biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipopolysaccharide core region biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane HDA PubMed 
Preferred Names
lipopolysaccharide core biosynthesis protein WaaS

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3804181..3805116 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418086.1 lipopolysaccharide core biosynthesis protein WaaS

    See identical proteins and their annotated locations for NP_418086.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A377E0H6
Nucleotide Protein
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