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lldD L-lactate dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948121, updated on 6-Jun-2024

Summary

Gene symbol
lldD
Gene description
L-lactate dehydrogenase
Primary source
ASAP:ABE-0011784
Locus tag
b3605
See related
ECOCYC:EG11963
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3595; lct; lctD
Summary
Arc regulon. [More information is available at EcoGene: EG11963]. L-lactate dehydrogenase is an FMN-dependent membrane-associated dehydrogenase . [More information is available at EcoCyc: EG11963].
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Genomic context

Sequence:
NC_000913.3 (3779827..3781017)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2810 domain-containing protein YibL Neighboring gene lactate/glycolate:H(+) symporter LldP Neighboring gene DNA-binding transcriptional dual regulator LldR Neighboring gene tRNA (cytidine/uridine-2'-O)-ribose methyltransferase Neighboring gene serine acetyltransferase

Pathways from PubChem

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables FMN binding IDA
Inferred from Direct Assay
more info
PubMed 
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 
enables L-lactate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables L-lactate dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lactate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on CH-OH group of donors IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within L-fucose catabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within aerobic respiration IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in lactate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lactate oxidation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lactate oxidation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3779827..3781017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418062.1 L-lactate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418062.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376MKZ5, A0A797I3W7
    Conserved Domains (1) summary
    PRK11197
    Location:1380
    lldD; L-lactate dehydrogenase; Provisional