U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

kdgK 2-dehydro-3-deoxygluconokinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948041, updated on 4-Apr-2024

Summary

Gene symbol
kdgK
Gene description
2-dehydro-3-deoxygluconokinase
Primary source
ASAP:ABE-0011519
Locus tag
b3526
See related
ECOCYC:EG12253
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3511; yhjI
Summary
KdgK is elevated 3-5X during growth at 4C (enabled by Oleispira antarctica Cpn10/60 transgene). [More information is available at EcoGene: EG12253]. 2-keto-3-deoxygluconokinase catalyzes the ATP-dependent phosphorylation of the first common intermediate in the D-glucuronate and D-galacturonate degradation pathways, 2-dehydro-3-deoxy-D-gluconate . [More information is available at EcoCyc: EG12253].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (3679419..3680348)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene AsmA family protein YhjG Neighboring gene c-di-GMP phosphodiesterase PdeH Neighboring gene peptidase M16 family protein YhjJ Neighboring gene C4 dicarboxylate/orotate:H(+) symporter

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2-dehydro-3-deoxygluconokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 2-dehydro-3-deoxygluconokinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 2-dehydro-3-deoxygluconokinase activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in D-galacturonate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within D-galacturonate catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in D-glucuronate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within D-glucuronate catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in DNA damage response IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in organic substance metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
2-dehydro-3-deoxygluconokinase
NP_417983.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3679419..3680348
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417983.2 2-dehydro-3-deoxygluconokinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417983.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AN08, A0A7D7DXF7, A0A8S7HUP5
    Conserved Domains (1) summary
    cd01166
    Location:4301
    KdgK; 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the ...