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hdeD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948024, updated on 24-Aug-2024

Summary

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Official Symbol
hdeD
Primary source
ASAP:ABE-0011467
Locus tag
b3511
See related
ECOCYC:EG11495
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3495; yhiA
Summary
EvgAS regulon. [More information is available at EcoGene: EG11495]. HdeD is required for the acid resistance phenotype exhibited upon overproduction of YdeO . [More information is available at EcoCyc: EG11495].
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Genomic context

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Sequence:
NC_000913.3 (3656995..3657567)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic acid stress chaperone HdeB Neighboring gene periplasmic acid stress chaperone HdeA Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional activator GadE

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Contrasting silencing mechanisms of the same target mRNA by two regulatory RNAs in Escherichia coli. Lalaouna D, et al. Nucleic Acids Res, 2018 Mar 16. PMID 29294085, Free PMC Article
  2. GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli. Hommais F, et al. Microbiology (Reading), 2004 Jan. PMID 14702398
  3. Physical map location of a set of Escherichia coli genes (hde) whose expression is affected by the nucleoid protein H-NS. Yoshida T, et al. J Bacteriol, 1993 Dec. PMID 8244952, Free PMC Article
  4. Products of the Escherichia coli acid fitness island attenuate metabolite stress at extremely low pH and mediate a cell density-dependent acid resistance. Mates AK, et al. J Bacteriol, 2007 Apr. PMID 17259322, Free PMC Article
  5. Anticipating an alkaline stress through the Tor phosphorelay system in Escherichia coli. Bordi C, et al. Mol Microbiol, 2003 Apr. PMID 12657056

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Both CyaR and RprA can block the translation initiation of hdeD but only CyaR induces mRNA decay.
    Title: Contrasting silencing mechanisms of the same target mRNA by two regulatory RNAs in Escherichia coli.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within response to pH IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
acid-resistance membrane protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3656995..3657567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417968.1 acid-resistance membrane protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417968.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAI9MER3
    Conserved Domains (1) summary
    PRK10209
    Location:1 → 190
    PRK10209; HdeD family acid-resistance protein
Nucleotide Protein
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