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nikC Ni(2(+)) ABC transporter membrane subunit NikC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947990, updated on 6-May-2021

Summary

Gene symbol
nikC
Gene description
Ni(2(+)) ABC transporter membrane subunit NikC
Primary source
ASAP:ABE-0011358
Locus tag
b3478
See related
ECOCYC:EG12077
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3462; hydC; hydD
Summary
Mutants display nickel-remediated formate hydrogen-lyase, hydrogenase, and hydrogenase-related fumarase defects. [More information is available at EcoGene: EG12077]. The NikABCDE ATP-dependent nickel (II) uptake system is a member of the ATP-Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG12077].
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Genomic context

Sequence:
NC_000913.3 (3616182..3617015)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene holo-[acyl carrier protein] synthase 2 Neighboring gene Ni(2(+)) ABC transporter periplasmic binding protein Neighboring gene Ni(2(+)) ABC transporter membrane subunit NikB Neighboring gene Ni(2(+)) ABC transporter ATP binding subunit NikD Neighboring gene Ni(2(+)) ABC transporter ATP binding subunit NikE Neighboring gene DNA-binding transcriptional repressor NikR

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ABC-type nickel transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables dipeptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nickel cation binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nickel cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables nickel cation transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ni(2(+)) ABC transporter membrane subunit NikC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3616182..3617015
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417935.1 Ni(2(+)) ABC transporter membrane subunit NikC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417935.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AFA9
    Conserved Domains (1) summary
    PRK10417
    Location:6277
    nikC; nickel transporter permease NikC; Provisional
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