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agaI putative deaminase AgaI [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947985, updated on 19-Sep-2024

Summary

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Official Symbol
agaI
Official Full Name
putative deaminase AgaI
Primary source
ECOCYC:G7636
Locus tag
b3141
See related
ASAP:ABE-0010317
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3129; yraG
Summary
Unlike other Escherichia coli strains, K-12 is unable to grow on N-acetylgalactosamine as a source of carbon and energy. [More information is available at EcoCyc: G7636].
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Genomic context

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Sequence:
NC_000913.3 (3286270..3287025)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene galactosamine-specific PTS enzyme IIB component Neighboring gene galactosamine-specific PTS enzyme IIC component Neighboring gene galactosamine-specific PTS enzyme IID component Neighboring gene putative fimbrial protein YraH Neighboring gene putative fimbrial chaperone YraI

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic analysis of the roles of agaA, agaI, and agaS genes in the N-acetyl-D-galactosamine and D-galactosamine catabolic pathways in Escherichia coli strains O157:H7 and C. Hu Z, et al. BMC Microbiol, 2013 May 1. PMID 23634833, Free PMC Article
  2. An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Reed JL, et al. Genome Biol, 2003. PMID 12952533, Free PMC Article
  3. Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli. Reizer J, et al. Microbiology (Reading), 1996 Feb. PMID 8932697
  4. Pathways for the utilization of N-acetyl-galactosamine and galactosamine in Escherichia coli. Brinkkötter A, et al. Mol Microbiol, 2000 Jul. PMID 10931310
  5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The agaI, nagB, and agaI nagB mutants were not affected in Aga and D-galactosamine utilization indicating that neither agaI nor nagB is involved in the deamination and isomerization of D-galactosamine-6-P.
    Title: Genetic analysis of the roles of agaA, agaI, and agaS genes in the N-acetyl-D-galactosamine and D-galactosamine catabolic pathways in Escherichia coli strains O157:H7 and C.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables galactosamine-6-phosphate isomerase activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables glucosamine-6-phosphate deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucosamine-6-phosphate deaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in N-acetylglucosamine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in N-acetylglucosamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in N-acetylneuraminate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glucosamine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative deaminase AgaI

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3286270..3287025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417610.1 putative deaminase AgaI [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417610.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7FDW0
    Conserved Domains (1) summary
    PRK09762
    Location:20 → 251
    PRK09762; galactosamine-6-phosphate isomerase; Provisional
Nucleotide Protein
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