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nikA Ni(2(+)) ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947981, updated on 23-Nov-2023

Summary

Gene symbol
nikA
Gene description
Ni(2(+)) ABC transporter periplasmic binding protein
Primary source
ASAP:ABE-0011354
Locus tag
b3476
See related
ECOCYC:EG12075
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3460; hydC; hydD
Summary
NikA binds hemin and protoporphyrin IX (Shepherd, 2007). [More information is available at EcoGene: EG12075]. NikA is the periplasmic binding component of the nickel ABC transporter in Escherichia coli. [More information is available at EcoCyc: EG12075].
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Genomic context

Sequence:
NC_000913.3 (3613667..3615241)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YhhT Neighboring gene holo-[acyl carrier protein] synthase 2 Neighboring gene Ni(2(+)) ABC transporter membrane subunit NikB Neighboring gene Ni(2(+)) ABC transporter membrane subunit NikC Neighboring gene Ni(2(+)) ABC transporter ATP binding subunit NikD Neighboring gene Ni(2(+)) ABC transporter ATP binding subunit NikE

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables heme binding IDA
Inferred from Direct Assay
more info
PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables metal cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nickel cation binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nickel cation binding IEA
Inferred from Electronic Annotation
more info
 
enables peptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transition metal ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within negative chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nickel cation import across plasma membrane NAS
Non-traceable Author Statement
more info
PubMed 
involved_in nickel cation transport IEA
Inferred from Electronic Annotation
more info
 
involved_in peptide transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ni(2(+)) ABC transporter periplasmic binding protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3613667..3615241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417933.1 Ni(2(+)) ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417933.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N8NF58
    Conserved Domains (1) summary
    TIGR02294
    Location:21520
    nickel_nikA; nickel ABC transporter, nickel/metallophore periplasmic binding protein