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pabA aminodeoxychorismate synthase subunit 2 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947873, updated on 12-Aug-2026
Official Symbol
pabA
Official Full Name
aminodeoxychorismate synthase subunit 2
Primary source
ECOCYC:EG10682
Locus tag
b3360
See related
ASAP:ABE-0010983
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3348
Summary
Component II provides the glutamine amidotransferase activity. [More information is available at EcoCyc: EG10682].
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Sequence:
NC_000913.3 (3490266..3490829, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YhfK Neighboring gene N-acetylornithine aminotransferase/N-succinyldiaminopimelate aminotransferase Neighboring gene protein YrfJ Neighboring gene putative adenosine monophosphate--protein transferase Fic Neighboring gene DUF2559 domain-containing protein YhfG Neighboring gene peptidyl-prolyl cis-trans isomerase A

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Biosynthesis of 4-aminobenzoate in Escherichia coli. Huang M, et al. J Bacteriol, 1970 Jun. PMID 4914080, Free PMC Article
  2. Nucleotide sequence of Escherichia coli pabA and its evolutionary relationship to trp(G)D. Kaplan JB, et al. J Mol Biol, 1983 Aug 15. PMID 6350604
  3. p-aminobenzoate synthesis in Escherichia coli: kinetic and mechanistic characterization of the amidotransferase PabA. Roux B, et al. Biochemistry, 1992 Aug 4. PMID 1637823
  4. Chorismate aminations: partial purification of Escherichia coli PABA synthase and mechanistic comparison with anthranilate synthase. Walsh CT, et al. Biochemistry, 1987 Jul 28. PMID 3311153
  5. Escherichia coli aminodeoxychorismate synthase: analysis of pabB mutations affecting catalysis and subunit association. Rayl EA, et al. Biochim Biophys Acta, 1996 Jun 7. PMID 8679677

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aminodeoxychorismate synthase activity EXP
Inferred from Experiment
more info
 PubMed 
enables aminodeoxychorismate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aminodeoxychorismate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables aminodeoxychorismate synthase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
contributes_to anthranilate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within 4-aminobenzoate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in L-tryptophan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in folic acid biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tetrahydrofolate biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in tetrahydrofolate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of aminodeoxychorismate synthase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of aminodeoxychorismate synthase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
Preferred Names
aminodeoxychorismate synthase subunit 2
NP_417819.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3490266..3490829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417819.1 aminodeoxychorismate synthase subunit 2

    See identical proteins and their annotated locations for NP_417819.1

    Status: REVIEWED

    Conserved Domains (1) summary
    PRK08007
    Location:1 → 187
    PRK08007; aminodeoxychorismate synthase component 2
Nucleotide Protein
Heading Accession and Version

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