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dacB peptidoglycan DD-endopeptidase DacB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947693, updated on 22-May-2022

Summary

Gene symbol
dacB
Gene description
peptidoglycan DD-endopeptidase DacB
Primary source
ASAP:ABE-0010458
Locus tag
b3182
See related
ECOCYC:EG10202
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3171
Summary
False positive lipoprotein prediction, verified SPI substrate. [More information is available at EcoGene: EG10202]. PBP4 is a penicillin-sensitive protein that catalyzes both D-alanyl-D-alanine carboxypeptidase and D-alanyl-D-alanine endopeptidase activities, though the former has been shown to occur at low levels. [More information is available at EcoCyc: EG10202].
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Genomic context

Sequence:
NC_000913.3 (3328963..3330396)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ribosome assembly factor YhbY Neighboring gene transcription elongation factor GreA Neighboring gene GTPase ObgE Neighboring gene putative transporter YhbE

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables carboxypeptidase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables endopeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables penicillin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables serine-type D-Ala-D-Ala carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type D-Ala-D-Ala carboxypeptidase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables serine-type carboxypeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables serine-type carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type carboxypeptidase activity ISM
Inferred from Sequence Model
more info
PubMed 
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within FtsZ-dependent cytokinesis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidoglycan metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within peptidoglycan metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 
involved_in response to antibiotic IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
peptidoglycan DD-endopeptidase DacB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3328963..3330396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417649.1 peptidoglycan DD-endopeptidase DacB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417649.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P24228
    Conserved Domains (1) summary
    PRK11113
    Location:1477
    PRK11113; D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional