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prpC 2-methylcitrate synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947528, updated on 25-Jan-2024

Summary

Gene symbol
prpC
Gene description
2-methylcitrate synthase
Primary source
ASAP:ABE-0001148
Locus tag
b0333
See related
ECOCYC:G6198
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0330; yahS; yzzD
Summary
Repressed during biofilm formation. [More information is available at EcoGene: EG11756]. Regulation has been described . [More information is available at EcoCyc: G6198].
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Genomic context

Sequence:
NC_000913.3 (350012..351181)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator PrpR Neighboring gene 2-methylisocitrate lyase Neighboring gene 2-methylcitrate dehydratase Neighboring gene propionyl-CoA synthetase

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2-methylcitrate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 2-methylcitrate synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 2-methylcitrate synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity, acyl groups converted into alkyl on transfer IEA
Inferred from Electronic Annotation
more info
 
enables citrate (Si)-synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables citrate (Si)-synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables citrate (Si)-synthase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables citrate synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in propionate metabolic process, methylcitrate cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within propionate metabolic process, methylcitrate cycle IDA
Inferred from Direct Assay
more info
PubMed 
involved_in propionate metabolic process, methylcitrate cycle IDA
Inferred from Direct Assay
more info
PubMed 
involved_in tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
2-methylcitrate synthase
NP_414867.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    350012..351181
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414867.1 2-methylcitrate synthase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414867.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376X4G5
    Conserved Domains (1) summary
    PRK12351
    Location:15388
    PRK12351; methylcitrate synthase; Provisional