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dkgA methylglyoxal reductase DkgA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947495, updated on 6-Jun-2024

Summary

Gene symbol
dkgA
Gene description
methylglyoxal reductase DkgA
Primary source
ASAP:ABE-0009892
Locus tag
b3012
See related
ECOCYC:G7565
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3004; yqhE
Summary
DkgA has been shown to have a stereoselective beta-keto ester reductase and methylglyxoal reductase activity. [More information is available at EcoCyc: G7565].
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Genomic context

Sequence:
NC_000913.3 (3156623..3157450)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator YqhC Neighboring gene NADPH-dependent aldehyde reductase YqhD Neighboring gene DUF3828 domain-containing protein YqhG Neighboring gene lipoprotein YqhH

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in L-ascorbic acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in methylglyoxal catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within methylglyoxal catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in small molecule metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
methylglyoxal reductase DkgA
NP_417485.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3156623..3157450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417485.4 methylglyoxal reductase DkgA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417485.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9ANZ1
    Conserved Domains (1) summary
    PRK11565
    Location:1275
    dkgA; 2,5-didehydrogluconate reductase DkgA