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emrA multidrug efflux pump membrane fusion protein EmrA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947166, updated on 19-Sep-2024

Summary

Official Symbol
emrA
Official Full Name
multidrug efflux pump membrane fusion protein EmrA
Primary source
ECOCYC:EG11354
Locus tag
b2685
See related
ASAP:ABE-0008838
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2679
Summary
EmrA is the membrane fusion protein for the EmrB multidrug efflux pump. [More information is available at EcoCyc: EG11354].
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Genomic context

Sequence:
NC_000913.3 (2811427..2812599)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-valine exporter, YgaZ component Neighboring gene L-valine exporter, YgaH component Neighboring gene DNA-binding transcriptional regulator MprA Neighboring gene multidrug efflux pump membrane subunit EmrB Neighboring gene S-ribosylhomocysteine lyase

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables bile acid transmembrane transporter activity EXP
Inferred from Experiment
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables xenobiotic transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of efflux pump complex NAS
Non-traceable Author Statement
more info
PubMed 
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in outer membrane-bounded periplasmic space ISM
Inferred from Sequence Model
more info
PubMed 
located_in periplasmic side of plasma membrane NAS
Non-traceable Author Statement
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
multidrug efflux pump membrane fusion protein EmrA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2811427..2812599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417170.1 multidrug efflux pump membrane fusion protein EmrA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417170.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A826PFZ7
    Conserved Domains (1) summary
    PRK15136
    Location:1390
    PRK15136; multidrug efflux MFS transporter periplasmic adaptor subunit EmrA