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idnO 5-keto-D-gluconate 5-reductase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947109, updated on 10-Oct-2019

Summary

Gene symbol
idnO
Gene description
5-keto-D-gluconate 5-reductase
Primary source
EcoGene:EG12540
Locus tag
b4266
See related
ASAP:ABE-0013971; ECOCYC:G7892
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4259; yjgU
Summary
The subunit structure of 5-keto-D-gluconate 5-reductase has not been determined. [More information is available at EcoCyc: G7892].

Genomic context

Sequence:
NC_000913.3 (4492587..4493351, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator IdnR Neighboring gene L-idonate/5-ketogluconate/gluconate transporter Neighboring gene L-idonate 5-dehydrogenase Neighboring gene D-gluconate kinase, thermosensitive

Pathways from BioSystems

  • L-idonate degradation, organism-specific biosystem (from BIOCYC)
    L-idonate degradation, organism-specific biosystemL-idonate can serve as the sole source of carbon for growth of E. coli. After transport into the cell, : L-IDONATE first undergoes dehydrogenation to : 5-DEHYDROGLUCONATE, followed by a reduction to...
  • L-idonate degradation, conserved biosystem (from BIOCYC)
    L-idonate degradation, conserved biosystemL-Idonate is catabolized via a pathway in which D-gluconate is an intermediate. L-Idonate is converted to D-gluconate by two consecutive oxidation and reduction reactions. D-Gluconate is then phosph...
  • ketogluconate metabolism, organism-specific biosystem (from BIOCYC)
    ketogluconate metabolism, organism-specific biosystemE. coli can utilize 2-keto-D-gluconate (2KDG) as the sole source of carbon, although it supports only very slow growth. The generation time on minimal medium containing 2KDG is nearly 28 hours . De...
  • ketogluconate metabolism, conserved biosystem (from BIOCYC)
    ketogluconate metabolism, conserved biosystemWhen the bacterium |FRAME: ORG-6226| is grown with |FRAME: 25-DIDEHYDRO-D-GLUCONATE| as the sole carbon and energy source it accumulates two stereoisomeric compounds: |FRAME: CPD-377| and |FRAME: CPD...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
gluconate 5-dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
gluconate 5-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
L-idonate catabolic process IEA
Inferred from Electronic Annotation
more info
 
L-idonate catabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
5-keto-D-gluconate 5-reductase
NP_418687.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4492587..4493351 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418687.1 5-keto-D-gluconate 5-reductase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418687.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A9P9
    Conserved Domains (1) summary
    PRK08085
    Location:1254
    PRK08085; gluconate 5-dehydrogenase; Provisional
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