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acpS holo-[acyl-carrier-protein] synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947037, updated on 6-May-2021

Summary

Gene symbol
acpS
Gene description
holo-[acyl-carrier-protein] synthase
Primary source
ASAP:ABE-0008433
Locus tag
b2563
See related
ECOCYC:EG10247
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
dpj; ECK2561
Summary
acpS(dpj) was demonstrated to be an essential gene (Takiff, 1992), consistent with the results of Baba (2006). [More information is available at EcoGene: EG10247]. The acpS gene encodes holo-[ACP] synthase, which transfers the 4-phosphopantetheine moiety of CoA to the apo-ACP to form holo-ACP, the active form of the carrier in lipid synthesis . [More information is available at EcoCyc: EG10247].
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Genomic context

Sequence:
NC_000913.3 (2700618..2700998, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene toxic peptide ShoB Neighboring gene ncRNA Neighboring gene pyridoxine 5'-phosphate synthase Neighboring gene DNA repair protein RecO

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables holo-[acyl-carrier-protein] synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables holo-[acyl-carrier-protein] synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
holo-[acyl-carrier-protein] synthase
NP_417058.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2700618..2700998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417058.1 holo-[acyl-carrier-protein] synthase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417058.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P24224
    Conserved Domains (1) summary
    PRK00070
    Location:2126
    acpS; 4'-phosphopantetheinyl transferase; Provisional
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