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hscB [Fe-S] cluster biosynthesis co-chaperone HscB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946995, updated on 23-Nov-2023

Summary

Gene symbol
hscB
Gene description
[Fe-S] cluster biosynthesis co-chaperone HscB
Primary source
ASAP:ABE-0008317
Locus tag
b2527
See related
ECOCYC:EG12131
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2524; yfhE
Summary
HscB is a co-chaperone that stimulates HscA (Hsc66) ATPase activity . [More information is available at EcoCyc: EG12131].
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Genomic context

Sequence:
NC_000913.3 (2658952..2659467, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene reduced ferredoxin Neighboring gene iron-sulfur cluster biosynthesis chaperone HscA Neighboring gene iron-sulfur cluster insertion protein IscA Neighboring gene scaffold protein for iron-sulfur cluster assembly

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATPase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
part_of iron-sulfur cluster transfer complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of iron-sulfur cluster transfer complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
[Fe-S] cluster biosynthesis co-chaperone HscB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2658952..2659467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417022.1 [Fe-S] cluster biosynthesis co-chaperone HscB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417022.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AFX1, A0A5B9AT87, A0A828GJN1
    Conserved Domains (1) summary
    PRK05014
    Location:1170
    hscB; co-chaperone HscB; Provisional