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dcyD D-cysteine desulfhydrase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946831, updated on 19-Sep-2024

Summary

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Official Symbol
dcyD
Official Full Name
D-cysteine desulfhydrase
Primary source
ECOCYC:G7038
Locus tag
b1919
See related
ASAP:ABE-0006389
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1918; yedO
Summary
dcyD is a non-essential gene. [More information is available at EcoGene: EG14038]. D-cysteine desulfhydrase is involved in utilization of D-cysteine as a source of sulfur. [More information is available at EcoCyc: G7038].
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Genomic context

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Sequence:
NC_000913.3 (1998494..1999480, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cystine ABC transporter ATP binding subunit Neighboring gene cystine ABC transporter membrane subunit Neighboring gene cystine ABC transporter periplasmic binding protein Neighboring gene DNA-binding transcriptional regulator FliZ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. D-Cysteine desulfhydrase of Escherichia coli. Purification and characterization. Nagasawa T, et al. Eur J Biochem, 1985 Dec 16. PMID 3908101
  2. Physiological comparison of D-cysteine desulfhydrase of Escherichia coli with 3-chloro-D-alanine dehydrochlorinase of Pseudomonas putida CR 1-1. Nagasawa T, et al. Arch Microbiol, 1988. PMID 3132906
  3. Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine. Soutourina J, et al. J Biol Chem, 2001 Nov 2. PMID 11527960
  4. Identification and functional analysis of Escherichia coli cysteine desulfhydrases. Awano N, et al. Appl Environ Microbiol, 2005 Jul. PMID 16000837, Free PMC Article
  5. A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map. Itoh T, et al. DNA Res, 1996 Dec 31. PMID 9097040

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 3-chloro-D-alanine dehydrochlorinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables D-cysteine desulfhydrase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables D-cysteine desulfhydrase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables D-cysteine desulfhydrase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within D-amino acid metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in D-amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within D-cysteine catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cellular response to sulfur starvation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within sulfur compound metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within sulfur utilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
D-cysteine desulfhydrase
NP_416429.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1998494..1999480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416429.4 D-cysteine desulfhydrase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416429.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376M6E2, A0A827QRF5, A0A828PIB5, A0A8H9XLV7, A0A8S7CQF7, A0A8S7TR17
    Conserved Domains (1) summary
    PRK03910
    Location:4 → 328
    PRK03910; D-cysteine desulfhydrase; Validated
Nucleotide Protein
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