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znuB Zn(2(+)) ABC transporter membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946372, updated on 26-Mar-2025

Summary

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Official Symbol
znuB
Official Full Name
Zn(2(+)) ABC transporter membrane subunit
Primary source
ECOCYC:EG12368
Locus tag
b1859
See related
ASAP:ABE-0006201
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1860; yebI
Summary
[More information is available at EcoCyc: EG12368].
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Genomic context

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Sequence:
NC_000913.3 (1943414..1944199)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene peptidoglycan endopeptidase MepM Neighboring gene Zn(2(+)) ABC transporter periplasmic binding protein Neighboring gene Zn(2(+)) ABC transporter ATP binding subunit Neighboring gene Holliday junction branch migration complex subunit RuvB Neighboring gene Holliday junction branch migration complex subunit RuvA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SoxS increases the expression of the zinc uptake system ZnuACB in an Escherichia coli murine pyelonephritis model. Warner DM, et al. J Bacteriol, 2012 Mar. PMID 22210763, Free PMC Article
  2. Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination. Shinagawa H, et al. J Bacteriol, 1988 Sep. PMID 2842314, Free PMC Article
  3. The zinc-responsive regulator Zur and its control of the znu gene cluster encoding the ZnuABC zinc uptake system in Escherichia coli. Patzer SI, et al. J Biol Chem, 2000 Aug 11. PMID 10816566
  4. Members of the Fur protein family regulate iron and zinc transport in E. coli and characteristics of the Fur-regulated fhuF protein. Hantke K. J Mol Microbiol Biotechnol, 2002 May. PMID 11931550
  5. ZupT is a Zn(II) uptake system in Escherichia coli. Grass G, et al. J Bacteriol, 2002 Feb. PMID 11790762, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This work implicates SoxS control of znuCB expression as a key factor in persistence of Escherichia coli in murine pyelonephritis.
    Title: SoxS increases the expression of the zinc uptake system ZnuACB in an Escherichia coli murine pyelonephritis model.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables high-affinity zinc transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in response to zinc ion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within zinc ion import across plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in zinc ion import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in zinc ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
  
part_of ATP-binding cassette (ABC) transporter complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Zn(2(+)) ABC transporter membrane subunit
NP_416373.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1943414..1944199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416373.1 Zn(2(+)) ABC transporter membrane subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416373.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A377BM00
    Conserved Domains (1) summary
    PRK09543
    Location:1 → 261
    znuB; zinc ABC transporter permease subunit ZnuB
Nucleotide Protein
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