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umuC DNA polymerase V catalytic protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946359, updated on 2-May-2024

Summary

Gene symbol
umuC
Gene description
DNA polymerase V catalytic protein
Primary source
ASAP:ABE-0003977
Locus tag
b1184
See related
ECOCYC:EG11056
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1172; uvm
Summary
ATPgammaS inhibits UmuC activity. [More information is available at EcoGene: EG11056]. The chaperones Hsp70 (DnaK) and Hsp60 (MopA) help fold UmuC into its functional form . [More information is available at EcoCyc: EG11056].
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Genomic context

Sequence:
NC_000913.3 (1231186..1232454)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hemolysin E Neighboring gene DNA polymerase V protein UmuD Neighboring gene protein thiol:quinone oxidoreductase DsbB Neighboring gene Na(+):H(+) antiporter NhaB

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP-dependent activity, acting on DNA IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-directed DNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA-directed DNA polymerase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in SOS response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in SOS response IDA
Inferred from Direct Assay
more info
PubMed 
involved_in SOS response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within SOS response IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in error-prone translesion synthesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within translesion synthesis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in translesion synthesis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of DNA polymerase V complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of DNA polymerase V complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
DNA polymerase V catalytic protein
NP_415702.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1231186..1232454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415702.1 DNA polymerase V catalytic protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415702.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6BBY9
    Conserved Domains (1) summary
    PRK03609
    Location:1422
    umuC; translesion error-prone DNA polymerase V subunit UmuC