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trpA tryptophan synthase subunit alpha [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946204, updated on 4-Feb-2024

Summary

Gene symbol
trpA
Gene description
tryptophan synthase subunit alpha
Primary source
ASAP:ABE-0004232
Locus tag
b1260
See related
ECOCYC:EG11024
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1254; try; tryp
Summary
otherPDB (S. typhimurium): [More information is available at EcoGene: EG11024]. The TrpA polypeptide (TSase ) functions as the subunit of the tetrameric (2-2) tryptophan synthase complex. [More information is available at EcoCyc: EG11024].
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Genomic context

Sequence:
NC_000913.3 (1316416..1317222, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF892 domain-containing protein YciF Neighboring gene stress-induced bacterial acidophilic repeat motifs-containing protein YciG Neighboring gene tryptophan synthase subunit beta Neighboring gene fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase Neighboring gene anthranilate synthase subunit TrpD Neighboring gene anthranilate synthase subunit TrpE

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular adaptor activity EXP
Inferred from Experiment
more info
PubMed 
contributes_to tryptophan synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables tryptophan synthase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
tryptophan synthase subunit alpha
NP_415776.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1316416..1317222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415776.1 tryptophan synthase subunit alpha [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415776.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7L7E6Z5, A0A8S7T3L1, A0AA46LN70
    Conserved Domains (1) summary
    TIGR00262
    Location:8263
    trpA; tryptophan synthase, alpha subunit