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trpA tryptophan synthase subunit alpha [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946204, updated on 10-Oct-2019

Summary

Gene symbol
trpA
Gene description
tryptophan synthase subunit alpha
Primary source
EcoGene:EG11024
Locus tag
b1260
See related
ASAP:ABE-0004232; ECOCYC:EG11024
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1254; try; tryp
Summary
otherPDB (S. typhimurium): [More information is available at EcoGene: EG11024]. The TrpA polypeptide (TSase ) functions as the subunit of the tetrameric (2-2) tryptophan synthase complex. [More information is available at EcoCyc: EG11024].

Genomic context

Sequence:
NC_000913.3 (1316416..1317222, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF892 domain-containing protein YciF Neighboring gene protein YciG Neighboring gene tryptophan synthase subunit beta Neighboring gene fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase Neighboring gene anthranilate synthase subunit TrpD Neighboring gene anthranilate synthase subunit TrpE

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
lyase activity IEA
Inferred from Electronic Annotation
more info
 
tryptophan synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Contributes_to tryptophan synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
tryptophan synthase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
aromatic amino acid family biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
aromatic amino acid family biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
tryptophan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tryptophan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
tryptophan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
tryptophan metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
chloroplast IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
tryptophan synthase subunit alpha
NP_415776.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1316416..1317222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415776.1 tryptophan synthase subunit alpha [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415776.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A877
    Conserved Domains (1) summary
    TIGR00262
    Location:8263
    trpA; tryptophan synthase, alpha subunit
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