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treA periplasmic trehalase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945757, updated on 19-Sep-2024

Summary

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Official Symbol
treA
Official Full Name
periplasmic trehalase
Primary source
ECOCYC:EG11017
Locus tag
b1197
See related
ASAP:ABE-0004021
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1185; osmA; tre
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Genomic context

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Sequence:
NC_000913.3 (1245679..1247376, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF04226 family protein YmgE Neighboring gene uncharacterized protein YcgY Neighboring gene dihydroxyacetone kinase subunit M Neighboring gene dihydroxyacetone kinase subunit L

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Total syntheses of casuarine and its 6-O-alpha-glucoside: complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families. Cardona F, et al. Chemistry, 2009. PMID 19123216
  2. Osmotic induction of the periplasmic trehalase in Escherichia coli K12: characterization of the treA gene promoter. Repoila F, et al. Mol Microbiol, 1991 Mar. PMID 1710760
  3. Synthesis, accumulation, and excretion of trehalose in osmotically stressed Escherichia coli K-12 strains: influence of amber suppressors and function of the periplasmic trehalase. Styrvold OB, et al. J Bacteriol, 1991 Feb. PMID 1825082, Free PMC Article
  4. Periplasmic trehalase from Escherichia coli--characterization and immobilization on spherisorb. Tourinho-dos-Santos CF, et al. Braz J Med Biol Res, 1994 Mar. PMID 8081287
  5. The Periplasmic Trehalase Affects Type 1 Fimbria Production and Virulence of Extraintestinal Pathogenic Escherichia coli Strain MT78. Pavanelo DB, et al. Infect Immun, 2018 Aug. PMID 29844238, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results show that the treA gene is needed for optimal production of type 1 fimbriae in extraintestinal pathogenic Escherichia coli strain MT78 and that loss of treA significantly reduces its cell invasion capacity and colonization of the bladder in a murine model of urinary tract infection.
    Title: The Periplasmic Trehalase Affects Type 1 Fimbria Production and Virulence of Extraintestinal Pathogenic Escherichia coli Strain MT78.
  2. N-terminus verified by Edman degradation on mature peptide
    Title: Analysis and DNA sequence of the osmoregulated treA gene encoding the periplasmic trehalase of Escherichia coli K12.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha,alpha-trehalase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha,alpha-trehalase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alpha,alpha-trehalase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular hyperosmotic response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cellular hyperosmotic response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in trehalose catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in trehalose catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within trehalose catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in trehalose metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
periplasmic trehalase
NP_415715.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1245679..1247376 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415715.1 periplasmic trehalase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415715.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376K0I5, A0A895NUX1
    Conserved Domains (1) summary
    PRK13271
    Location:1 → 565
    treA; alpha,alpha-trehalase TreA
Nucleotide Protein
Heading Accession and Version

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