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deoD purine nucleoside phosphorylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945654, updated on 22-Aug-2021

Summary

Gene symbol
deoD
Gene description
purine nucleoside phosphorylase
Primary source
ASAP:ABE-0014379
Locus tag
b4384
See related
ECOCYC:EG10222
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4376; pup
Summary
DeoD has reversible purine nucleoside phosphorylase (PNP) activity with broad substrate specificity; however, it does not act on xanthosine or pyrimidine nucleosides . [More information is available at EcoCyc: EG10222].
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Genomic context

Sequence:
NC_000913.3 (4620883..4621602)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene thymidine phosphorylase Neighboring gene phosphopentomutase Neighboring gene toxin YjjJ Neighboring gene lipoate--protein ligase A

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables pentosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables purine-nucleoside phosphorylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables purine-nucleoside phosphorylase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables purine-nucleoside phosphorylase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
purine nucleoside phosphorylase
NP_418801.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4620883..4621602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418801.1 purine nucleoside phosphorylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418801.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0ABP8
    Conserved Domains (1) summary
    PRK05819
    Location:2236
    deoD; DeoD-type purine-nucleoside phosphorylase
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