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ribD fused diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945620, updated on 2-May-2024

Summary

Gene symbol
ribD
Gene description
fused diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Primary source
ASAP:ABE-0001441
Locus tag
b0414
See related
ECOCYC:EG11321
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0408; nusII; ribG; ybaE
Summary
The ribD gene encodes a bifunctional enzyme that catalyzes the second (deamination) and third (reduction) steps in the riboflavin biosynthesis pathway. [More information is available at EcoCyc: EG11321].
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Genomic context

Sequence:
NC_000913.3 (433455..434558)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative lipoprotein YajI Neighboring gene NrdR transcriptional repressor Neighboring gene 6,7-dimethyl-8-ribityllumazine synthase Neighboring gene transcription antitermination protein NusB

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
fused diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
NP_414948.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    433455..434558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414948.1 fused diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414948.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A485JIQ4, A0A6N0IHG2, A0A8S7E9V5
    Conserved Domains (1) summary
    PRK10786
    Location:1367
    ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD