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cdsA CDP-diglyceride synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944876, updated on 22-Sep-2022

Summary

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Gene symbol
cdsA
Gene description
CDP-diglyceride synthetase
Primary source
ASAP:ABE-0000600
Locus tag
b0175
See related
ECOCYC:EG10139
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cds; ECK0174
Summary
CdsA binds RNaseE. [More information is available at EcoGene: EG10139].
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Genomic context

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Sequence:
NC_000913.3 (195677..196534)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] Neighboring gene intramembrane zinc metalloprotease RseP Neighboring gene outer membrane protein assembly factor BamA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CDP-diacylglycerol synthase of microorganisms. Dowhan W. Biochim Biophys Acta, 1997 Sep 4. PMID 9370328
  2. pH-sensitive CDP-diglyceride synthetase mutants of Escherichia coli: phenotypic suppression by mutations at a second site. Ganong BR, et al. J Bacteriol, 1983 Feb. PMID 6296051, Free PMC Article
  3. Phosphatidic acid accumulation in the membranes of Escherichia coli mutants defective in CDP-diglyceride synthetase. Ganong BR, et al. J Biol Chem, 1980 Feb 25. PMID 6243645
  4. Cytidine triphosphate: phosphatidic acid cytidyltransferase in Escherichia coli. Carter JR Jr. J Lipid Res, 1968 Nov. PMID 4879388
  5. Purification and properties of the membrane-bound CDP-diglyceride synthetase from Escherichia coli. Sparrow CP, et al. J Biol Chem, 1985 Oct 5. PMID 2995359

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by GO

Function Evidence Code Pubs
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidate cytidylyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables phosphatidate cytidylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatidate cytidylyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in CDP-diacylglycerol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
acts_upstream_of_or_within CDP-diacylglycerol biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within CDP-diacylglycerol biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within CDP-diacylglycerol biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CDP-diglyceride synthetase
NP_414717.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    195677..196534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414717.2 CDP-diglyceride synthetase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414717.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0ABG1
    Conserved Domains (1) summary
    PRK11624
    Location:1 → 285
    cdsA; phosphatidate cytidylyltransferase
Nucleotide Protein
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Gene LinkOut

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Other Literature Sources
Molecular Biology Databases