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cdsA CDP-diglyceride synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944876, updated on 17-Jul-2025
Official Symbol
cdsA
Official Full Name
CDP-diglyceride synthetase
Primary source
ECOCYC:EG10139
Locus tag
b0175
See related
ASAP:ABE-0000600
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cds; ECK0174
Summary
CdsA binds RNaseE. [More information is available at EcoGene: EG10139].
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Sequence:
NC_000913.3 (195677..196534)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] Neighboring gene intramembrane zinc metalloprotease RseP Neighboring gene outer membrane protein assembly factor BamA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. CDP-diacylglycerol synthase of microorganisms. Dowhan W. Biochim Biophys Acta, 1997 Sep 4. PMID 9370328
  2. pH-sensitive CDP-diglyceride synthetase mutants of Escherichia coli: phenotypic suppression by mutations at a second site. Ganong BR, et al. J Bacteriol, 1983 Feb. PMID 6296051, Free PMC Article
  3. Phosphatidic acid accumulation in the membranes of Escherichia coli mutants defective in CDP-diglyceride synthetase. Ganong BR, et al. J Biol Chem, 1980 Feb 25. PMID 6243645
  4. Cytidine triphosphate: phosphatidic acid cytidyltransferase in Escherichia coli. Carter JR Jr. J Lipid Res, 1968 Nov. PMID 4879388
  5. Partial purification and properties of CTP:phosphatidic acid cytidylyltransferase from membranes of Escherichia coli. Langley KE, et al. J Bacteriol, 1978 Oct. PMID 30751, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables phosphatidate cytidylyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidate cytidylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in CDP-diacylglycerol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within CDP-diacylglycerol biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within CDP-diacylglycerol biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
CDP-diglyceride synthetase
NP_414717.2

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    195677..196534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414717.2 CDP-diglyceride synthetase

    See identical proteins and their annotated locations for NP_414717.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5B9AL74, A0A7A6TYV8
    Conserved Domains (1) summary
    PRK11624
    Location:1 → 285
    cdsA; phosphatidate cytidylyltransferase
Nucleotide Protein
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