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X X protein [ Hepatitis B virus ]

Gene ID: 944566, updated on 18-Jul-2024

Summary

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Gene symbol
X
Gene description
X protein
Locus tag
HBVgp3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Hepatitis B virus (strain: ayw)
Lineage
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Blubervirales; Hepadnaviridae; Orthohepadnavirus
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Genomic context

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Sequence:
NC_003977.2 (1376..1840)

NC_003977.2Genomic Context describing neighboring genes Neighboring gene large envelope protein;middle envelope protein;small envelope protein Neighboring gene polymerase Neighboring gene capsid protein;pre-capsid protein Neighboring gene polymerase Neighboring gene large envelope protein;middle envelope protein;small envelope protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003977.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. JNK/c-Jun pathway activation is essential for HBx-induced IL-35 elevation to promote persistent HBV infection.
    Title: JNK/c-Jun pathway activation is essential for HBx-induced IL-35 elevation to promote persistent HBV infection.
  2. Hepatitis B Virus X Protein Inhibits the Expression of Barrier To Autointegration factor1 via Upregulating miR-203 Expression in Hepatic Cells.
    Title: Hepatitis B Virus X Protein Inhibits the Expression of Barrier To Autointegration factor1 via Upregulating miR-203 Expression in Hepatic Cells.
  3. Identification of critical residues in the regulatory protein HBx for Smc5/6 interaction and hepatitis B virus production.
    Title: Identification of critical residues in the regulatory protein HBx for Smc5/6 interaction and hepatitis B virus production.
  4. HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-kappaB Signaling, to Promote HBV Replication.
    Title: HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
  5. Spatiotemporal modulation of SMAD4 by HBx is required for cellular proliferation in hepatitis B-related liver cancer.
    Title: Spatiotemporal modulation of SMAD4 by HBx is required for cellular proliferation in hepatitis B-related liver cancer.
  6. Hepatitis B virus X protein mediated epigenetic alterations in the pathogenesis of hepatocellular carcinoma.
    Title: Hepatitis B virus X protein mediated epigenetic alterations in the pathogenesis of hepatocellular carcinoma.
  7. Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA.
    Title: Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA.
  8. HBX suppresses PTEN to promote the malignant progression of hepatocellular carcinoma through mi-R155 activation.
    Title: HBX suppresses PTEN to promote the malignant progression of hepatocellular carcinoma through mi-R155 activation.
  9. Novel X gene point mutations in chronic hepatitis B and HBV related cirrhotic patients.
    Title: Novel X gene point mutations in chronic hepatitis B and HBV related cirrhotic patients.
  10. HBx increases chromatin accessibility and ETV4 expression to regulate dishevelled-2 and promote HCC progression.
    Title: HBx increases chromatin accessibility and ETV4 expression to regulate dishevelled-2 and promote HCC progression.
Submit: New GeneRIF Correction See all GeneRIFs (430)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

regulatory

  • Loc: 1592-1602
  • Loc: 1775-1794
  • Loc: 1826-1836
  • Loc: 1834-1839

General protein information

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Preferred Names
X protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003977.2 Reference assembly

    Range
    1376..1840
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009173867.1 X protein [Hepatitis B virus]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A075T2U3, A0A075T2U6, A0A075T5M0, A0A075T610, A0A075T6T5, A0A075TD39, A0A0S3CUJ6, A0A1B2G2S2, A0A286QXD6, A0A2P1E6D4, C9WDD5, G9G967, G9I645, H6UMZ1, H6UN39, I1Z8G1, Q2F514, Q80IS1
Nucleotide Protein
Heading Accession and Version

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