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Bcl2l13 BCL2 like 13 [ Mus musculus (house mouse) ]

Gene ID: 94044, updated on 1-Mar-2024

Summary

Official Symbol
Bcl2l13provided by MGI
Official Full Name
BCL2 like 13provided by MGI
Primary source
MGI:MGI:2136959
See related
Ensembl:ENSMUSG00000009112 AllianceGenome:MGI:2136959
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mil1; Mil-1; BCL-RAMBO; E430016C20Rik
Summary
Predicted to act upstream of or within apoptotic process and regulation of apoptotic process. Located in mitochondrion. Orthologous to human BCL2L13 (BCL2 like 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 9.6), subcutaneous fat pad adult (RPKM 9.3) and 28 other tissues See more
Orthologs
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Genomic context

See Bcl2l13 in Genome Data Viewer
Location:
6 F1; 6 57.01 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (120813167..120869803)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (120836206..120892842)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit E1 Neighboring gene STARR-positive B cell enhancer ABC_E1709 Neighboring gene STARR-positive B cell enhancer ABC_E6479 Neighboring gene ribosomal protein S27 pseudogene Neighboring gene predicted gene, 38889 Neighboring gene STARR-seq mESC enhancer starr_17194 Neighboring gene STARR-positive B cell enhancer ABC_E8126 Neighboring gene STARR-positive B cell enhancer ABC_E10407 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120880485-120880722 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120884294-120884494 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit G1 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120885601-120885784 Neighboring gene STARR-positive B cell enhancer ABC_E6480 Neighboring gene BH3 interacting domain death agonist Neighboring gene STARR-positive B cell enhancer ABC_E11335 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120907410-120907630 Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 3 Neighboring gene predicted gene, 43915

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC38758

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
acts_upstream_of_or_within regulation of apoptotic process RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
Component Evidence Code Pubs
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in mitochondrion HDA PubMed 

General protein information

Preferred Names
bcl-2-like protein 13
Names
BCL2-like 13 (apoptosis facilitator)
bcl2-L-13
mitochondria located 1 homolog
protein Mil1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153516.2NP_705736.1  bcl-2-like protein 13

    See identical proteins and their annotated locations for NP_705736.1

    Status: VALIDATED

    Source sequence(s)
    AC083894, BC029016
    Consensus CDS
    CCDS20485.1
    UniProtKB/Swiss-Prot
    P59017, Q543S1
    UniProtKB/TrEMBL
    Q3UGC5
    Related
    ENSMUSP00000009256.3, ENSMUST00000009256.4
    Conserved Domains (1) summary
    pfam00452
    Location:101197
    Bcl-2; Apoptosis regulator proteins, Bcl-2 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    120813167..120869803
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506814.3XP_006506877.1  bcl-2-like protein 13 isoform X1

    UniProtKB/TrEMBL
    Q3UGC5
    Conserved Domains (2) summary
    pfam00452
    Location:67163
    Bcl-2; Apoptosis regulator proteins, Bcl-2 family
    pfam17061
    Location:194317
    PARM
  2. XM_017321842.2XP_017177331.1  bcl-2-like protein 13 isoform X2

    UniProtKB/TrEMBL
    Q3UGC5
    Conserved Domains (1) summary
    pfam00452
    Location:65161
    Bcl-2; Apoptosis regulator proteins, Bcl-2 family