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MRFAP1L2 Morf4 family associated protein 1 like 2 [ Homo sapiens (human) ]

Gene ID: 93622, updated on 1-Mar-2024

Summary

Official Symbol
MRFAP1L2provided by HGNC
Official Full Name
Morf4 family associated protein 1 like 2provided by HGNC
Primary source
HGNC:HGNC:25109
See related
Ensembl:ENSG00000170846
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UPP
Expression
Ubiquitous expression in brain (RPKM 12.2), ovary (RPKM 8.2) and 24 other tissues See more
Orthologs
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Genomic context

See MRFAP1L2 in Genome Data Viewer
Location:
4p16.1
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (6674075..6676047)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (6648973..6651114)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (6675802..6677774)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900840 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15234 Neighboring gene long intergenic non-protein coding RNA 2482 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:6674796-6675404 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15235 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:6684859-6685361 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:6685913-6686414 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:6690316-6691515 Neighboring gene long intergenic non-protein coding RNA 2481 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:6694289-6694826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:6695136-6695872 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:6695873-6696608 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:6697811-6698573 Neighboring gene S100 calcium binding protein P

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • AC093323.3

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of cell cycle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
MORF4 family associated protein 1 like 2
Names
MORF4 family-associated protein 1-like protein UPP
putative MORF4 family-associated protein 1-like protein UPP

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138699.3NP_619644.1  MORF4 family associated protein 1 like 2

    Status: VALIDATED

    Source sequence(s)
    AC093323
    UniProtKB/Swiss-Prot
    B2RBV5
    Related
    ENSP00000493540.1, ENST00000635031.2
    Conserved Domains (1) summary
    pfam15155
    Location:1119
    MRFAP1; MORF4 family-associated protein1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    6674075..6676047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047416419.1XP_047272375.1  MORF4 family associated protein 1 like 2 isoform X1

    UniProtKB/Swiss-Prot
    B2RBV5
    Related
    ENSP00000495193.1, ENST00000307533.10
  2. XM_047416420.1XP_047272376.1  MORF4 family associated protein 1 like 2 isoform X1

    UniProtKB/Swiss-Prot
    B2RBV5
    Related
    ENSP00000493702.1, ENST00000444232.3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    6648973..6651114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054351268.1XP_054207243.1  MORF4 family associated protein 1 like 2 isoform X1

    UniProtKB/Swiss-Prot
    B2RBV5
  2. XM_054351269.1XP_054207244.1  MORF4 family associated protein 1 like 2 isoform X1

    UniProtKB/Swiss-Prot
    B2RBV5