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GPR37L1 G protein-coupled receptor 37 like 1 [ Homo sapiens (human) ]

Gene ID: 9283, updated on 7-Jun-2020

Summary

Official Symbol
GPR37L1provided by HGNC
Official Full Name
G protein-coupled receptor 37 like 1provided by HGNC
Primary source
HGNC:HGNC:14923
See related
Ensembl:ENSG00000170075 MIM:617630
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ETBRLP2; ETBR-LP-2; ET(B)R-LP-2
Expression
Biased expression in brain (RPKM 18.1) and colon (RPKM 0.5) See more
Orthologs

Genomic context

See GPR37L1 in Genome Data Viewer
Location:
1q32.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (202118669..202133592)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (202092029..202098634)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene FOXA motif-containing MPRA enhancer 200 Neighboring gene uncharacterized LOC105371684 Neighboring gene cysteine rich protein 1 pseudogene 3 Neighboring gene CRISPRi-validated cis-regulatory element chr1.10703 Neighboring gene uncharacterized LOC105371683 Neighboring gene ADP ribosylation factor like GTPase 8A Neighboring gene protein tyrosine phosphatase non-receptor type 7 Neighboring gene protein tyrosine phosphatase receptor type V, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled peptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled peptide receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
peptide binding IPI
Inferred from Physical Interaction
more info
PubMed 
prosaposin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
NOT prosaposin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
ciliary membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
G-protein coupled receptor 37-like 1
Names
endothelin B receptor-like protein 2
endothelin type b receptor-like protein 2
prosaposin receptor GPR37L1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004767.5NP_004758.3  G-protein coupled receptor 37-like 1 precursor

    See identical proteins and their annotated locations for NP_004758.3

    Status: VALIDATED

    Source sequence(s)
    AK222639, AL050068, AL592300
    Consensus CDS
    CCDS1420.1
    UniProtKB/Swiss-Prot
    O60883
    Related
    ENSP00000356251.4, ENST00000367282.6
    Conserved Domains (1) summary
    pfam00001
    Location:147397
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    202118669..202133592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510158.2XP_011508460.1  G-protein coupled receptor 37-like 1 isoform X1

    Conserved Domains (1) summary
    pfam00001
    Location:22210
    7tm_1; 7 transmembrane receptor (rhodopsin family)
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