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GLYATL1 glycine-N-acyltransferase like 1 [ Homo sapiens (human) ]

Gene ID: 92292, updated on 5-Jan-2022

Summary

Official Symbol
GLYATL1provided by HGNC
Official Full Name
glycine-N-acyltransferase like 1provided by HGNC
Primary source
HGNC:HGNC:30519
See related
Ensembl:ENSG00000166840 MIM:614761
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GNAT; GATF-C
Summary
Enables glutamine N-acyltransferase activity. Involved in glutamine metabolic process. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in kidney (RPKM 74.7), liver (RPKM 64.2) and 1 other tissue See more
Orthologs
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Genomic context

See GLYATL1 in Genome Data Viewer
Location:
11q12.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (58905481..58957062)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (58672871..58724547)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene translation machinery associated 16 homolog pseudogene 1 Neighboring gene glycine-N-acyltransferase like 2 Neighboring gene glycine-N-acyltransferase like 1 pseudogene 2 Neighboring gene uncharacterized LOC283194 Neighboring gene protein kinase cAMP-dependent type II regulatory subunit beta pseudogene Neighboring gene glycine-N-acyltransferase like 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ26507, FLJ34646, FLJ60524, MGC15397, MGC15937

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables N-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glutamine N-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glutamine N-acyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables glycine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in glutamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glutamine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glycine N-acyltransferase-like protein 1
Names
acyl-CoA:glycine N-acyltransferase-like protein 1
glutamine N-acyltransferase
NP_001207423.1
NP_001207425.1
NP_001341628.1
NP_001376640.1
NP_001376641.1
NP_001376642.1
NP_001376643.1
NP_001376644.1
NP_001376645.1
NP_001376646.1
NP_001376647.1
NP_542392.2
XP_011543656.1
XP_011543657.1
XP_011543658.1
XP_011543659.1
XP_011543660.1
XP_011543661.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001220494.4NP_001207423.1  glycine N-acyltransferase-like protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001207423.1

    Status: VALIDATED

    Source sequence(s)
    AP001636, AP001652, KF459756
    Consensus CDS
    CCDS55768.1
    UniProtKB/Swiss-Prot
    Q969I3
    UniProtKB/TrEMBL
    A9ZM15
    Related
    ENSP00000322223.4, ENST00000317391.8
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  2. NM_001220496.4NP_001207425.1  glycine N-acyltransferase-like protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001207425.1

    Status: VALIDATED

    Source sequence(s)
    AP001636, KF459756
    Consensus CDS
    CCDS55768.1
    UniProtKB/Swiss-Prot
    Q969I3
    UniProtKB/TrEMBL
    A9ZM15
    Related
    ENSP00000479741.1, ENST00000612196.1
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  3. NM_001354699.4NP_001341628.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, AP001652, KF459756
    Consensus CDS
    CCDS55768.1
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  4. NM_001389711.2NP_001376640.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, AP001652, KF459756
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  5. NM_001389712.2NP_001376641.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, KF459756
    Related
    ENSP00000436116.2, ENST00000532726.6
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  6. NM_001389713.2NP_001376642.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, KF459756
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  7. NM_001389714.2NP_001376643.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, AP001652, KF459756
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  8. NM_001389715.2NP_001376644.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, KF459756
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  9. NM_001389716.2NP_001376645.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, KF459756
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  10. NM_001389717.2NP_001376646.1  glycine N-acyltransferase-like protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001636, AP001652, KF459756
    Conserved Domains (2) summary
    pfam08444
    Location:208296
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1207
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  11. NM_001389718.2NP_001376647.1  glycine N-acyltransferase-like protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AP001636, AP001652, KF459756
    Related
    ENSP00000510029.1, ENST00000685442.1
    Conserved Domains (2) summary
    pfam06021
    Location:1166
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
    cl17182
    Location:167255
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
  12. NM_080661.6NP_542392.2  glycine N-acyltransferase-like protein 1 isoform 1

    See identical proteins and their annotated locations for NP_542392.2

    Status: VALIDATED

    Source sequence(s)
    AP001636, KF459756
    Consensus CDS
    CCDS31556.1
    UniProtKB/Swiss-Prot
    Q969I3
    Related
    ENSP00000300079.5, ENST00000300079.9
    Conserved Domains (2) summary
    pfam08444
    Location:239327
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:51238
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    58905481..58957062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011545357.2XP_011543659.1  glycine N-acyltransferase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011543659.1

    Conserved Domains (2) summary
    pfam08444
    Location:231319
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:43230
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  2. XM_011545355.2XP_011543657.1  glycine N-acyltransferase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011543657.1

    Conserved Domains (2) summary
    pfam08444
    Location:231319
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:43230
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  3. XM_011545356.2XP_011543658.1  glycine N-acyltransferase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011543658.1

    Conserved Domains (2) summary
    pfam08444
    Location:231319
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:43230
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  4. XM_011545354.2XP_011543656.1  glycine N-acyltransferase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011543656.1

    Related
    ENSP00000508694.1, ENST00000689150.1
    Conserved Domains (2) summary
    pfam08444
    Location:231319
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:43230
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  5. XM_011545358.3XP_011543660.1  glycine N-acyltransferase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011543660.1

    Conserved Domains (2) summary
    pfam08444
    Location:231319
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:43230
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  6. XM_011545359.2XP_011543661.1  glycine N-acyltransferase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011543661.1

    Conserved Domains (2) summary
    pfam08444
    Location:231319
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:43230
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
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