U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

UBTD2 ubiquitin domain containing 2 [ Homo sapiens (human) ]

Gene ID: 92181, updated on 12-Aug-2022

Summary

Official Symbol
UBTD2provided by HGNC
Official Full Name
ubiquitin domain containing 2provided by HGNC
Primary source
HGNC:HGNC:24463
See related
Ensembl:ENSG00000168246 MIM:610174; AllianceGenome:HGNC:24463
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DCUBP
Summary
Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis (RPKM 21.6), endometrium (RPKM 12.8) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See UBTD2 in Genome Data Viewer
Location:
5q35.1
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (172209646..172284117, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (172749942..172824056, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (171636650..171710768, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene serine/threonine kinase 10 Neighboring gene EF-hand calcium binding domain 9 Neighboring gene small nucleolar RNA SNORA57 Neighboring gene uncharacterized LOC100288254 Neighboring gene Kruppel like factor 3 pseudogene 1 Neighboring gene SH3 and PX domains 2B Neighboring gene Sharpr-MPRA regulatory region 10478

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC30022

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ubiquitin domain-containing protein 2
Names
ubiquitin-like protein SB72

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152277.3NP_689490.2  ubiquitin domain-containing protein 2

    See identical proteins and their annotated locations for NP_689490.2

    Status: VALIDATED

    Source sequence(s)
    AC008671, AC024561
    Consensus CDS
    CCDS4379.2
    UniProtKB/Swiss-Prot
    Q8TDQ3, Q8WUN7
    UniProtKB/TrEMBL
    B3KMW8
    Related
    ENSP00000377381.2, ENST00000393792.3
    Conserved Domains (2) summary
    cd17121
    Location:151225
    Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
    pfam16455
    Location:30132
    UBD; Ubiquitin-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    172209646..172284117 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047417875.1XP_047273831.1  ubiquitin domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B2R886
  2. XM_047417876.1XP_047273832.1  ubiquitin domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B2R886
  3. XM_017010022.2XP_016865511.1  ubiquitin domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q8WUN7
    UniProtKB/TrEMBL
    B2R886
    Conserved Domains (2) summary
    cd17121
    Location:107181
    Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
    pfam16455
    Location:188
    UBD; Ubiquitin-binding domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    172749942..172824056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)