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PAGE5 PAGE family member 5 [ Homo sapiens (human) ]

Gene ID: 90737, updated on 11-Jun-2021

Summary

Official Symbol
PAGE5provided by HGNC
Official Full Name
PAGE family member 5provided by HGNC
Primary source
HGNC:HGNC:29992
See related
Ensembl:ENSG00000158639 MIM:301009
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT16; CT16.1; CT16.2; GAGEE1; PAGE-5
Summary
This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. The encoded protein may protect cells from programmed cell death. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jan 2015]
Expression
Restricted expression toward testis (RPKM 6.1) See more
Orthologs
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Genomic context

See PAGE5 in Genome Data Viewer
Location:
Xp11.21
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (55220346..55224108)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (55246779..55250541)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene X antigen family member 3-like Neighboring gene MT-RNR2 like 10 Neighboring gene small nucleolar RNA, H/ACA box 109 Neighboring gene PAGE family member 3 Neighboring gene PAGE family member 5 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
P antigen family member 5
Names
P antigen family, member 5 (prostate associated)
cancer/testis antigen 16.1
cancer/testis antigen family 16, member 1
cancer/testis antigen family 16, member 2
g antigen family E member 1
prostate-associated gene 5 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013435.3NP_001013453.1  P antigen family member 5 isoform 2

    See identical proteins and their annotated locations for NP_001013453.1

    Status: REVIEWED

    Source sequence(s)
    AL158819, BP429046, BQ437151
    Consensus CDS
    CCDS35306.1
    UniProtKB/Swiss-Prot
    Q96GU1
    Related
    ENSP00000364093.3, ENST00000374955.8
    Conserved Domains (1) summary
    pfam05831
    Location:1109
    GAGE; GAGE protein
  2. NM_130467.5NP_569734.2  P antigen family member 5 isoform 1

    See identical proteins and their annotated locations for NP_569734.2

    Status: REVIEWED

    Source sequence(s)
    AL158819, BC009230, BP429046, BQ437151
    Consensus CDS
    CCDS14368.1
    UniProtKB/Swiss-Prot
    Q96GU1
    Related
    ENSP00000289619.5, ENST00000289619.9
    Conserved Domains (1) summary
    pfam05831
    Location:21126
    GAGE; GAGE protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    55220346..55224108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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