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DCAF15 DDB1 and CUL4 associated factor 15 [ Homo sapiens (human) ]

Gene ID: 90379, updated on 17-Jun-2019

Summary

Official Symbol
DCAF15provided by HGNC
Official Full Name
DDB1 and CUL4 associated factor 15provided by HGNC
Primary source
HGNC:HGNC:25095
See related
Ensembl:ENSG00000132017
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C19orf72
Expression
Broad expression in testis (RPKM 20.9), bone marrow (RPKM 11.3) and 24 other tissues See more
Orthologs

Genomic context

See DCAF15 in Genome Data Viewer
Location:
19p13.12
Exon count:
13
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (13952474..13961449)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (14063319..14072256)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene nanos C2HC-type zinc finger 3 Neighboring gene microRNA 181d Neighboring gene chromosome 19 open reading frame 57 Neighboring gene coiled-coil and C2 domain containing 1A Neighboring gene podocan like 1 Neighboring gene regulatory factor X1 Neighboring gene uncharacterized LOC107985309 Neighboring gene relaxin 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC99481

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
protein ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Cul4-RING E3 ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Cul4-RING E3 ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
DDB1- and CUL4-associated factor 15

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138353.3NP_612362.2  DDB1- and CUL4-associated factor 15

    See identical proteins and their annotated locations for NP_612362.2

    Status: VALIDATED

    Source sequence(s)
    BC018894, BC080575, HY003563
    Consensus CDS
    CCDS32926.1
    UniProtKB/Swiss-Prot
    Q66K64
    Related
    ENSP00000254337.5, ENST00000254337.10
    Conserved Domains (2) summary
    pfam14939
    Location:51259
    DCAF15_WD40; DDB1-and CUL4-substrate receptor 15, WD repeat
    cl26464
    Location:274381
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    13952474..13961449
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_021160022.1 Reference GRCh38.p13 PATCHES

    Range
    164315..173290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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