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FER1L5 fer-1 like family member 5 [ Homo sapiens (human) ]

Gene ID: 90342, updated on 27-Aug-2024

Summary

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Official Symbol
FER1L5provided by HGNC
Official Full Name
fer-1 like family member 5provided by HGNC
Primary source
HGNC:HGNC:19044
See related
Ensembl:ENSG00000249715 MIM:620883; AllianceGenome:HGNC:19044
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable calcium ion binding activity and calcium-dependent phospholipid binding activity. Predicted to be involved in several processes, including myeloid cell activation involved in immune response; negative regulation of phagocytosis; and plasma membrane organization. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in T-tubule and cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 3.3) and prostate (RPKM 0.1) See more
Orthologs
mouse all
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Genomic context

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Location:
2q11.2
Exon count:
56
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (96642764..96704883)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (97149398..97211521)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (97308501..97370620)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11771 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11772 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16221 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:97204265-97204810 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16222 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:97219546-97220071 Neighboring gene AT-rich interaction domain 5A Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:97230045-97230545 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:97230616-97231116 Neighboring gene KAT8 regulatory NSL complex subunit 3 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:97273727-97274926 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16223 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11773 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:97326800-97327300 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:97327301-97327801 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:97351655-97352380 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:97359457-97359958 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:97360677-97361221 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:97361222-97361765 Neighboring gene lectin, mannose binding 2 like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:97404177-97405116 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:97405117-97406054 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16224 Neighboring gene H3K4me1 hESC enhancers GRCh37_chr2:97426686-97427275 and GRCh37_chr2:97427276-97427864 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11775 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16226 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16227 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:97435174-97436108 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16228 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16229 Neighboring gene cyclin and CBS domain divalent metal cation transport mediator 4 Neighboring gene microRNA 3127

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Psychiatric GWAS Consortium Bipolar Disorder Working Group. Nat Genet, 2011 Sep 18. PMID 21926972, Free PMC Article
  2. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
  3. TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile. Dendoncker K, et al. Proc Natl Acad Sci U S A, 2019 Jun 25. PMID 31182584, Free PMC Article
  4. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512
  5. Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Fasci D, et al. Mol Cell Proteomics, 2018 Oct. PMID 30021884, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of neurotransmitter secretion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
fer-1-like protein 5
Names
fer-1-like 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293083.2 → NP_001280012.1  fer-1-like protein 5

    Status: VALIDATED

    Source sequence(s)
    AC068539, AC079754, AL133022, AY461813, BC126368, DB083434, DW009988
    Consensus CDS
    CCDS77438.1
    UniProtKB/Swiss-Prot
    A0A096LNV2, A0AVI2, Q17RH2, Q6ZU24
    UniProtKB/TrEMBL
    A0A286YFD1
    Related
    ENSP00000485238.1, ENST00000624922.6
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1487 → 1610
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1722 → 1854
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 324
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1872 → 1986
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    96642764..96704883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512110.3 → XP_011510412.1  fer-1-like protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1487 → 1610
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1731 → 1863
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1881 → 1996
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

  2. XM_011512122.3 → XP_011510424.1  fer-1-like protein 5 isoform X12

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (10) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1487 → 1610
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1731 → 1863
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    cl14603
    Location:331 → 468
    C2; C2 domain

  3. XM_011512119.3 → XP_011510421.1  fer-1-like protein 5 isoform X10

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1452 → 1556
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1677 → 1809
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1827 → 1942
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

  4. XM_011512111.3 → XP_011510413.1  fer-1-like protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1486 → 1609
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1730 → 1862
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1880 → 1995
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

  5. XM_011512114.3 → XP_011510416.1  fer-1-like protein 5 isoform X5

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1486 → 1609
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1721 → 1853
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1871 → 1986
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

  6. XM_017005222.2 → XP_016860711.1  fer-1-like protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A286YFD1

  7. XM_011512117.3 → XP_011510419.1  fer-1-like protein 5 isoform X8

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1452 → 1575
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1696 → 1828
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1846 → 1961
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

  8. XM_011512113.3 → XP_011510415.1  fer-1-like protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A286YFD1
    Related
    ENSP00000493220.1, ENST00000623019.5
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1074 → 1209
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1485 → 1608
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1729 → 1861
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1879 → 1994
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

  9. XM_011512116.3 → XP_011510418.1  fer-1-like protein 5 isoform X7

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1047 → 1182
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1458 → 1581
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1702 → 1834
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:751 → 809
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 736
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1852 → 1967
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:331 → 468
    C2; C2 domain

  10. XM_011512115.3 → XP_011510417.1  fer-1-like protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (11) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1053 → 1188
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1464 → 1587
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1708 → 1840
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:757 → 815
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:670 → 742
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:596 → 643
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1858 → 1973
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:341 → 445
    C2; C2 domain

  11. XM_011512118.3 → XP_011510420.1  fer-1-like protein 5 isoform X9

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (9) summary
    cd04017
    Location:1036 → 1171
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1447 → 1570
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1691 → 1823
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:740 → 798
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:653 → 725
    FerB; FerB (NUC096) domain
    pfam08165
    Location:579 → 626
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1841 → 1956
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:164 → 250
    C2; C2 domain

  12. XM_011512120.3 → XP_011510422.1  fer-1-like protein 5 isoform X11

    UniProtKB/TrEMBL
    A0A286YFD1
    Conserved Domains (10) summary
    cd04011
    Location:94 → 203
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1006 → 1141
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1417 → 1540
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08374
    Location:1661 → 1793
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:710 → 768
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:623 → 695
    FerB; FerB (NUC096) domain
    pfam08151
    Location:203 → 244
    FerI; FerI (NUC094) domain
    pfam08165
    Location:549 → 596
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1811 → 1926
    Ferlin_C; Ferlin C-terminus
    cl14603
    Location:261 → 398
    C2; C2 domain

  13. XM_011512125.3 → XP_011510427.1  fer-1-like protein 5 isoform X14

    Conserved Domains (8) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    cl14603
    Location:331 → 468
    C2; C2 domain

  14. XM_011512126.3 → XP_011510428.1  fer-1-like protein 5 isoform X15

    Conserved Domains (8) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    cl14603
    Location:331 → 468
    C2; C2 domain

  15. XM_011512127.3 → XP_011510429.1  fer-1-like protein 5 isoform X16

    Conserved Domains (8) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    cl14603
    Location:331 → 468
    C2; C2 domain

  16. XM_011512128.4 → XP_011510430.1  fer-1-like protein 5 isoform X17

    Conserved Domains (8) summary
    cd04011
    Location:164 → 273
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1076 → 1211
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd08373
    Location:5 → 134
    C2A_Ferlin; C2 domain first repeat in Ferlin
    smart00693
    Location:780 → 838
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:693 → 765
    FerB; FerB (NUC096) domain
    pfam08151
    Location:273 → 314
    FerI; FerI (NUC094) domain
    pfam08165
    Location:619 → 666
    FerA; FerA (NUC095) domain
    cl14603
    Location:331 → 468
    C2; C2 domain

  17. XM_011512124.3 → XP_011510426.1  fer-1-like protein 5 isoform X13

    Conserved Domains (7) summary
    cd04017
    Location:605 → 740
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1016 → 1139
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08374
    Location:1260 → 1392
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:309 → 367
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:222 → 294
    FerB; FerB (NUC096) domain
    pfam08165
    Location:148 → 195
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1410 → 1525
    Ferlin_C; Ferlin C-terminus

  18. XM_017005223.3 → XP_016860712.1  fer-1-like protein 5 isoform X13

    Conserved Domains (7) summary
    cd04017
    Location:605 → 740
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04037
    Location:1016 → 1139
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08374
    Location:1260 → 1392
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:309 → 367
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:222 → 294
    FerB; FerB (NUC096) domain
    pfam08165
    Location:148 → 195
    FerA; FerA (NUC095) domain
    pfam16165
    Location:1410 → 1525
    Ferlin_C; Ferlin C-terminus

  19. XM_017005224.2 → XP_016860713.1  fer-1-like protein 5 isoform X18

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    97149398..97211521
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054344425.1 → XP_054200400.1  fer-1-like protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A286YFD1

  2. XM_054344436.1 → XP_054200411.1  fer-1-like protein 5 isoform X12

    UniProtKB/TrEMBL
    A0A286YFD1

  3. XM_054344434.1 → XP_054200409.1  fer-1-like protein 5 isoform X10

    UniProtKB/TrEMBL
    A0A286YFD1

  4. XM_054344427.1 → XP_054200402.1  fer-1-like protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A286YFD1

  5. XM_054344429.1 → XP_054200404.1  fer-1-like protein 5 isoform X5

    UniProtKB/TrEMBL
    A0A286YFD1

  6. XM_054344426.1 → XP_054200401.1  fer-1-like protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A286YFD1

  7. XM_054344432.1 → XP_054200407.1  fer-1-like protein 5 isoform X8

    UniProtKB/TrEMBL
    A0A286YFD1

  8. XM_054344428.1 → XP_054200403.1  fer-1-like protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A286YFD1

  9. XM_054344431.1 → XP_054200406.1  fer-1-like protein 5 isoform X7

    UniProtKB/TrEMBL
    A0A286YFD1

  10. XM_054344430.1 → XP_054200405.1  fer-1-like protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A286YFD1

  11. XM_054344433.1 → XP_054200408.1  fer-1-like protein 5 isoform X9

    UniProtKB/TrEMBL
    A0A286YFD1

  12. XM_054344435.1 → XP_054200410.1  fer-1-like protein 5 isoform X11

    UniProtKB/TrEMBL
    A0A286YFD1

  13. XM_054344439.1 → XP_054200414.1  fer-1-like protein 5 isoform X14

  14. XM_054344440.1 → XP_054200415.1  fer-1-like protein 5 isoform X15

  15. XM_054344441.1 → XP_054200416.1  fer-1-like protein 5 isoform X16

  16. XM_054344442.1 → XP_054200417.1  fer-1-like protein 5 isoform X17

  17. XM_054344437.1 → XP_054200412.1  fer-1-like protein 5 isoform X13

  18. XM_054344438.1 → XP_054200413.1  fer-1-like protein 5 isoform X13

  19. XM_054344443.1 → XP_054200418.1  fer-1-like protein 5 isoform X18

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001077400.1: Suppressed sequence

    Description
    NM_001077400.1: This RefSeq was permanently suppressed because the CDS was partial, and the transcript was incompletely processed at its 5' end.

  2. NM_001113382.1: Suppressed sequence

    Description
    NM_001113382.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0AVI2.3 GenPept UniProtKB/Swiss-Prot:A0AVI2

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials