Format

Send to:

Choose Destination

TGIF2LX TGFB induced factor homeobox 2 like X-linked [ Homo sapiens (human) ]

Gene ID: 90316, updated on 11-Jun-2021

Summary

Official Symbol
TGIF2LXprovided by HGNC
Official Full Name
TGFB induced factor homeobox 2 like X-linkedprovided by HGNC
Primary source
HGNC:HGNC:18570
See related
Ensembl:ENSG00000153779 MIM:300411
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TGIFLX
Summary
This gene encodes a member of the TALE/TGIF homeobox family of transcription factors. Testis-specific expression suggests that this gene may play a role in spermatogenesis. A homolog of this gene lies within the male specific region of chromosome Y, in a block of sequence that is thought to be the result of a large X-to-Y transposition. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 5.8) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See TGIF2LX in Genome Data Viewer
Location:
Xq21.31
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (89921908..89922883)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (89176907..89177882)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102724150 Neighboring gene sorcin pseudogene 2 Neighboring gene STAU2 pseudogene 1 Neighboring gene USP12 pseudogene X-linked

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

Associated conditions

Description Tests
Genetically distinct subsets within ANCA-associated vasculitis.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC34726

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
homeobox protein TGIF2LX
Names
TGF-beta-induced transcription factor 2-like protein
TGFB-induced factor 2-like protein, X-linked
TGFB-induced factor 2-like, X-linked
TGIF-like on the X

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138960.4NP_620410.3  homeobox protein TGIF2LX

    See identical proteins and their annotated locations for NP_620410.3

    Status: REVIEWED

    Source sequence(s)
    AL590041
    Consensus CDS
    CCDS14459.1
    UniProtKB/Swiss-Prot
    Q8IUE1
    Related
    ENSP00000355119.4, ENST00000283891.6
    Conserved Domains (1) summary
    pfam05920
    Location:68107
    Homeobox_KN; Homeobox KN domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    89921908..89922883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center