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PAGE1 PAGE family member 1 [ Homo sapiens (human) ]

Gene ID: 8712, updated on 11-Jun-2021

Summary

Official Symbol
PAGE1provided by HGNC
Official Full Name
PAGE family member 1provided by HGNC
Primary source
HGNC:HGNC:4107
See related
Ensembl:ENSG00000068985 MIM:300288
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AL5; CT16.3; GAGE-9; GAGEB1; PAGE-1
Summary
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. Unlike the other gene family members, this gene does not encode an antigenic peptide. Nothing is presently known about the function of this protein. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 6.3) See more
Orthologs
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Genomic context

See PAGE1 in Genome Data Viewer
Location:
Xp11.23
Exon count:
6
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (49687447..49696019, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (49452050..49460587, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene voltage dependent anion channel 1 pseudogene 2 Neighboring gene spalt like transcription factor 1 pseudogene 1 Neighboring gene PAGE family member 4 Neighboring gene USP27X divergent transcript

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
P antigen family member 1
Names
G antigen 9
G antigen family B member 1
G antigen, family B, 1 (prostate associated)
P antigen family, member 1 (prostate associated)
prostate associated gene 1
prostate-associated gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012550.1 RefSeqGene

    Range
    5010..13547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_003785.4NP_003776.2  P antigen family member 1

    See identical proteins and their annotated locations for NP_003776.2

    Status: REVIEWED

    Source sequence(s)
    AC231643, BC004861, BU941413
    Consensus CDS
    CCDS14327.1
    UniProtKB/Swiss-Prot
    O75459
    Related
    ENSP00000365320.3, ENST00000376150.4
    Conserved Domains (1) summary
    pfam05831
    Location:198
    GAGE; GAGE protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    49687447..49696019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011543998.2XP_011542300.1  P antigen family member 1 isoform X1

    See identical proteins and their annotated locations for XP_011542300.1

    UniProtKB/Swiss-Prot
    O75459
    Conserved Domains (1) summary
    pfam05831
    Location:198
    GAGE; GAGE protein
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