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clmA ANTH domain-containing protein [ Dictyostelium discoideum AX4 ]

Gene ID: 8621557, updated on 18-Sep-2024

Summary

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Official Symbol
clmA
Official Full Name
ANTH domain-containing protein
Primary source
dictyBase:DDB_G0278685
Locus tag
DDB_G0278685
See related
AmoebaDB:DDB_G0278685; VEuPathDB:DDB_G0278685
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales; Dictyosteliaceae; Dictyostelium
Old locus tag
DDBDRAFT_0218102; DDBDRAFT_0235311; DDB_0218102; DDB_0235311
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Genomic context

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Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_007089.4 (852176..854714, complement)

Chromosome 3 - NC_007089.4Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene phosphopantothenoylcysteine decarboxylase Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007089.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The monomeric clathrin assembly protein, AP180, regulates contractile vacuole size in Dictyostelium discoideum. Stavrou I, et al. Mol Biol Cell, 2006 Dec. PMID 17050736, Free PMC Article
  2. Purification of clathrin heavy and light chain from Dictyostelium discoideum. Riddelle-Spencer KS, et al. Protein Expr Purif, 1997 Dec. PMID 9425628
  3. AP180-mediated trafficking of Vamp7B limits homotypic fusion of Dictyostelium contractile vacuoles. Wen Y, et al. Mol Biol Cell, 2009 Oct. PMID 19692567, Free PMC Article
  4. Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum. Bogdanovic A, et al. Biochem J, 2002 Nov 15. PMID 12175335, Free PMC Article
  5. The genome of the social amoeba Dictyostelium discoideum. Eichinger L, et al. Nature, 2005 May 5. PMID 15875012, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AP180 regulates contractile vacuole morphology and activity in Dictyostelium.
    Title: The monomeric clathrin assembly protein, AP180, regulates contractile vacuole size in Dictyostelium discoideum.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables 1-phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 1-phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables SNARE binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables clathrin binding IEA
Inferred from Electronic Annotation
more info
  
enables clathrin heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-4,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in clathrin coat assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in clathrin-dependent endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in clathrin-dependent endocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within contractile vacuole organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within hypotonic response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within intracellular water homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in vesicle budding from membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
part_of clathrin adaptor complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of clathrin complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in clathrin-coated pit IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in clathrin-coated pit IEA
Inferred from Electronic Annotation
more info
  
is_active_in clathrin-coated vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in clathrin-coated vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in clathrin-coated vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in contractile vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ANTH domain-containing protein
Names
clathrin assembly protein AP180

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007089.4 Reference assembly

    Range
    852176..854714 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_637260.1 → XP_642352.1  ANTH domain-containing protein [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_642352.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q54Y50
    Conserved Domains (1) summary
    cl02544
    Location:19 → 277
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
Nucleotide Protein
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